192436-83-2

Basic information

• Product Name: 4-BROMO-N-METHOXY-N-METHYLBENZAMIDE
• Synonyms: 4-BROMO-N-METHOXY-N-METHYLBENZAMIDE;4-[Methoxy(methyl)carbamoyl]bromobenzene
• CAS NO: 192436-83-2
• Molecular Formula: C₉H₁₀BrNO₂
• Molecular Weight: 244.09
• Mol File: 192436-83-2.mol
• Article Data: 37

Chemical Properties

• Boiling Point: 351.534 °C at 760 mmHg
• Flash Point: 166.402 °C
• Appearance: /
• Density: 1.459 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.5680 to 1.5720
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-BROMO-N-METHOXY-N-METHYLBENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-N-METHOXY-N-METHYLBENZAMIDE(192436-83-2)
• EPA Substance Registry System: 4-BROMO-N-METHOXY-N-METHYLBENZAMIDE(192436-83-2)

Safety Data

• Hazardous Substances Data: 192436-83-2(Hazardous Substances Data)

Usage

General Description

4-BROMO-N-METHOXY-N-METHYLBENZAMIDE is a chemical compound with the molecular formula C9H10BrNO2. It is a white solid that is used in the research and development of pharmaceuticals and agrochemicals. 4-BROMO-N-METHOXY-N-METHYLBENZAMIDE has a bromine atom, a methoxy group, and a methyl group attached to a benzamide backbone. It is known for its potential as a building block in the synthesis of various drug molecules and is also used as an intermediate in organic synthesis. Its properties and structure make it valuable in the study and production of new compounds for potential pharmaceutical and agricultural applications.

InChI:InChI=1/C9H10BrNO2/c1-11(13-2)9(12)7-3-5-8(10)6-4-7/h3-6H,1-2H3

Upstream product

• 619-42-1 4-methoxycarbonylphenyl bromide 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 201230-82-2 carbon monoxide 
• 589-87-7 1,4-bromoiodobenzene 
• 13939-06-5 molybdenum hexacarbonyl 
• 321970-34-7 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonic acid 4-bromophenyl ester 
• 99-90-1 para-bromoacetophenone 
• 1380243-00-4 3-(4-bromobenzoyl) oxazolidin-2-one 
• 586-76-5 4-Bromobenzoic acid 
• 1117-97-1 N,0-dimethylhydroxylamine 
• 586-75-4 4-chlorobenzoyl chloride 

Downstream Products

• 131895-07-3 1-(4-bromophenyl)-3-methylbutan-1-one 
• 161581-93-7 (4-bromo-phenyl)-(3-fluoro-4-methoxy-phenyl)-methanone 
• 4160-65-0 (4-bromophenyl)(thien-2-yl)methanone 
• 2138-34-3 1-(4-bromo-phenyl)-3-dimethylamino-propan-1-one 
• 14548-45-9 (4-bromophenyl)-pyridin-3-yl-methanone 
• 1314313-99-9 (3Z,6Z)-3-(3-(4-bromobenzoyl)benzylidene)-6-((5-tert-butyl-1H-imidazol-4-yl)methylene)piperazine-2,5-dione 
• 1385033-74-8 C₁₄H₉BrO₂ 
• 216506-62-6 4-(3-(4-bromophenyl)-1-methyl-1H-pyrazol-4-yl)pyridine 
• 1422842-08-7 4-(5-(4-bromophenyl)-1-methyl-1H-pyrazol-4-yl)pyridine 
• 1422842-10-1 C₁₅H₁₃N₃S 
• 1422842-13-4 C₁₅H₁₃N₃S 
• 1422841-43-7 C₂₆H₂₂N₄OS 
• 1422841-45-9 C₂₆H₂₂N₄OS 
• 1422841-48-2 C₂₆H₂₂N₄OS 

Relevant articles and documents

Poly(vinyl ketone)s by controlled boron group transfer polymerization (BGTP)

(Figure Presented) Boron can do it! Readily prepared catecholboron enolates act as regulators in the controlled radical polymerization of alkyl and aryl vinyl ketones. Control is achieved by an unprecedented reversible radical boron group transfer (BGT) between enoyl radicals (see scheme). Polymers with M n-1 and a polydispersity index of 1.3 can be obtained by this process.

NOVEL COMPOUNDS HAVING ANTI-INFLAMMATORY ACTIVITY AS P38 MAP KINASE INHIBITOR

The present invention relates to novel compounds exhibiting anti-inflammatory activity. The compound of the present invention plays a critical role in the production of inflammatory prodrug (pro-inflammatory cytokines) and has an excellent inhibitory effect on p38 MAPK, which is known to cause inflammatory diseases, and thus can be used as a therapeutic agent for inflammatory diseases.

Synthesis of various acylating agents directly from carboxylic acids

A straightforward synthesis of acylating reagents such as Weinreb and MAP amides from aromatic, aliphatic carboxylic acids, and amino acids using PPh3/NBS combination is described. A chemo-selective modification of the carboxylic acid group into Weinreb amide in the presence of more reactive aldehydes and ketones is presented. All reactions were performed at ambient temperature under air using undried commercial grade solvent. Furthermore, the present methodology could be performed at a gram scale under inert-free reaction conditions. In addition, 7-azaindoline amide auxiliary (used for catalytic asymmetric aldol- and Mannich-type reactions), which behaves like Weinreb amide is also synthesized under similar reaction conditions.