107412-71-5

Basic information

• Product Name: 3'-METHYL[1,1'-BIPHENYL]-2-CARBOXYLIC ACID
• Synonyms: 3'-METHYL[1,1'-BIPHENYL]-2-CARBOXYLIC ACID;AKOS BAR-0261;CHEMBRDG-BB 4400421;RARECHEM AL BE 1353;3'-methylbiphenyl-2-carboxylic acid(SALTDATA: FREE);2-Carboxy-3'-methylbiphenyl, 2-(3-Methylphenyl)benzoic acid;2-(3-Methylphenyl)benzoic acid;3'-methylbiphenyl-2-carboxylic acid
• CAS NO: 107412-71-5
• Molecular Formula: C₁₄H₁₂O₂
• Molecular Weight: 212.24
• Mol File: 107412-71-5.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 349.1 °C at 760 mmHg
• Flash Point: 163.3 °C
• Appearance: /
• Density: 1.156 g/cm³
• CAS DataBase Reference: 3'-METHYL[1,1'-BIPHENYL]-2-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-METHYL[1,1'-BIPHENYL]-2-CARBOXYLIC ACID(107412-71-5)
• EPA Substance Registry System: 3'-METHYL[1,1'-BIPHENYL]-2-CARBOXYLIC ACID(107412-71-5)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 107412-71-5(Hazardous Substances Data)

Usage

General Description

3'-Methyl[1,1'-biphenyl]-2-carboxylic acid is a chemical compound with a molecular formula C15H12O2. It is a carboxylic acid derivative of biphenyl, containing a methyl group attached to the 3' position of the biphenyl ring. This chemical is commonly used in the synthesis of various pharmaceutical and organic compounds, and it has been found to exhibit anti-inflammatory and antioxidant properties. It is also used as a building block in the production of dyes, fragrances, and polymer materials. The compound's precise applications and potential benefits make it an important intermediate in organic synthesis and drug development.

Upstream product

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Downstream Products

• 168047-35-6 (5-{4-[(3'-methyl-biphenyl-2-carbonyl)-amino]-benzoyl}-2-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]diazepin-1-yl)-acetic acid 
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• 1246739-34-3 5-(3-methylphenyl)-1,2,3,4-tetraphenylnaphthalene 

Relevant articles and documents

An improved protocol for ligandless Suzuki-Miyaura coupling in water

Using a reverse order of addition of reagents, PdCl2 and Pd(OAc)2 are efficient catalysts for the Suzuki-Miyaura reactions in water. The ligandless and mild conditions, the high stability of the catalytic system, short reaction time and good to excellent yields are important features of this protocol.

Palladium-catalyzed intramolecular aromatic C-H acylation of 2-arylbenzoyl fluorides

The catalytic intramolecular cyclization of acyl fluorides using a Pd(OAc)2/PCy3 system is described. A wide range of 2-arylbenzoyl fluoride derivatives can be used as fluorenone precursors and the reaction proceeds via an intramolecular coupling between aromatic C-H bonds with acyl C-F bonds. The reaction can be applied to the synthesis of indenofluorenedione derivatives and to the construction of other molecules with fivemembered rings.

Facile preparation of 3,4-benzocoumarins from 2-arylbenzoic acids with NCS and NAI

– Treatment of 2-arylbenzoic acids with N-chlorosuccinimide (NCS) and NaI at 70 °C under fluorescent lighting condition gave the corresponding 3,4-benzocoumarins in good yields under transition-metal-free condition. It was found that the reactivity of NCS

Silver-Catalyzed C(sp2)-H Functionalization/C-O Cyclization Reaction at Room Temperature

Silver-catalyzed C(sp2)-H functionalization/C-O cyclization has been developed. The scalable reaction proceeds at room temperature in an open flask. The present method exhibits good functional-group compatibility because of the mild reaction conditions. Using a AgNO3 catalyst and a (NH4)2S2O8 oxidant in CH2Cl2/H2O solvent, various lactones are obtained in good to excellent yields. A kinetic isotope effect (KIE) study indicates that the reaction may occur via a radical process.