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107416-50-2

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107416-50-2 Usage

Description

PHENYL-PIPERIDIN-1-YL-ACETIC ACID HYDROCHLORIDE, commonly known as loperamide hydrochloride, is a synthetic opioid receptor agonist that serves as an effective antidiarrheal medication. It operates by decelerating the intestinal motility, thereby diminishing the frequency and urgency of bowel movements. This chemical exhibits a high affinity for mu-opioid receptors in the intestine, which is instrumental in its therapeutic action. It is crucial to administer this medication as prescribed to avoid the risk of overdose and adverse effects, making it a valuable asset in the management of diarrhea.

Uses

Used in Pharmaceutical Industry:
PHENYL-PIPERIDIN-1-YL-ACETIC ACID HYDROCHLORIDE is used as an antidiarrheal agent for its ability to slow down intestinal movement, which helps in reducing the frequency and urgency of bowel movements. This makes it a suitable treatment for diarrhea, providing relief to patients experiencing this condition.
Used in Medical Treatments:
PHENYL-PIPERIDIN-1-YL-ACETIC ACID HYDROCHLORIDE is utilized as a therapeutic agent for managing diarrhea due to its high affinity for mu-opioid receptors in the intestine, which contributes to its effectiveness in controlling intestinal motility and alleviating the symptoms of diarrhea. It is important to follow the prescribed dosage to prevent misuse and potential adverse effects.

Check Digit Verification of cas no

The CAS Registry Mumber 107416-50-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,7,4,1 and 6 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 107416-50:
(8*1)+(7*0)+(6*7)+(5*4)+(4*1)+(3*6)+(2*5)+(1*0)=102
102 % 10 = 2
So 107416-50-2 is a valid CAS Registry Number.

107416-50-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name Phenyl-piperidin-1-yl-acetic acid hydrochloride

1.2 Other means of identification

Product number -
Other names 2-phenyl-2-piperidin-1-ylacetic acid,hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:107416-50-2 SDS

107416-50-2Relevant articles and documents

Straightforward α-Amino Nitrile Synthesis Through Mo(CO)6-Catalyzed Reductive Functionalization of Carboxamides

Trillo, Paz,Slagbrand, Tove,Adolfsson, Hans

, p. 12347 - 12351 (2018/09/10)

The selective reduction of amides into an intermediate hemiaminal catalyzed by Mo(CO)6 together with the inexpensive and easy to handle TMDS (1,1,3,3-tetramethyldisiloxane) as reducing agent, followed by subsequent trapping of the hemiaminal with a cyanide source, allows for the straightforward synthesis of α-amino nitriles. The methodology presented here, displays high levels of chemoselectivity allowing for the reduction of amides in the presence of functional groups such as ketones, imines, aldehydes, and acids, which affords a simple route for the synthesis of α-amino nitriles with a broad scope of functionalities in high yields. Furthermore, the applicability of this methodology is demonstrated by scale up experiments and by derivatization of the target compounds into synthetically interesting products. The selective cyanation is successfully applied in late stage functionalizations of amide containing drugs and prolinol derivatives.

QUINUCLIDINE ESTERS OF 1-AZAHETEROCYCLYLACETIC ACID AS ANTIMUSCARINIC AGENTS, PROCESS FOR THEIR PREPARATION AND MEDICINAL COMPOSITIONS THEREOF

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Page/Page column 27, (2013/07/19)

The invention relates to compounds of formula (I), wherein A, R1, R2, X, m and n are as defined in the specification, as selective M3 receptor antagonists, process for their preparation, composition comprising them and the therapeutic use thereof. Said co

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