107558-26-9

Basic information

• Product Name: Methyl 4'-nitro-[1,1'-biphenyl]-3-carboxylate
• Synonyms: Methyl 4'-nitro-[1,1'-biphenyl]-3-carboxylate
• CAS NO: 107558-26-9
• Molecular Formula: C14H11NO4
• Molecular Weight: 257.24144
• Mol File: 107558-26-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Methyl 4'-nitro-[1,1'-biphenyl]-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 4'-nitro-[1,1'-biphenyl]-3-carboxylate(107558-26-9)
• EPA Substance Registry System: Methyl 4'-nitro-[1,1'-biphenyl]-3-carboxylate(107558-26-9)

Safety Data

• Hazardous Substances Data: 107558-26-9(Hazardous Substances Data)

Upstream product

• 480425-35-2 methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate 
• 586-78-7 para-nitrophenyl bromide 
• 67-56-1 methanol 
• 729-01-1 4'-nitrobiphenyl-3-carboxylic acid 
• 25487-66-5 3-Carboxyphenylboronic acid 
• 636-98-6 p-nitrobenzene iodide 
• 99769-19-4 [3-(methoxycarbonyl)phenyl]boronic acid 

Downstream Products

• 400747-22-0 methyl 4' amino-[1,1'-biphenyl]-3-carboxylate 
• 1360630-39-2 methyl 4'-(6-cyano-2-naphthamido)biphenyl-3-carboxylate 
• 1360630-40-5 4'-(6-cyano-2-naphthamido)biphenyl-3-carboxylic acid 
• 1360630-41-6 methyl 4'-(6-methoxy-2-naphthamido)biphenyl-3-carboxylate 
• 1360630-48-3 methyl 4'-(6-chloro-2-naphthamido)biphenyl-3-carboxylate 
• 1360630-49-4 methyl 4'-(6-bromo-2-naphthamido)biphenyl-3-carboxylate 
• 1360630-50-7 methyl 4'-(6-amino-2-naphthamido)biphenyl-3-carboxylate 
• 1360630-51-8 methyl 4'-(naphthalene-2-sulfonamido)biphenyl-3-carboxylate 
• 1360630-55-2 methyl 4'-(6-methoxynaphthalene-2-sulfonamido)biphenyl-3-carboxylate 
• 729-01-1 4'-nitrobiphenyl-3-carboxylic acid 

Relevant articles and documents

Synthesis and evaluation of non-basic inhibitors of urokinase-type plasminogen activator (uPA)

Recent drug discovery programs targeting urokinase plasminogen activator (uPA) have resulted in nonpeptidic inhibitors consisting of amidine or guanidine functional groups attached to aromatic or heteroaromatic scaffolds. There is a general problem of poor oral bioavailability of these charged inhibitors. In this paper, we report the synthesis and evaluation of a series of naphthamide and naphthalene sulfonamides as uPA inhibitors containing non-basic groups as substitute for amidine or guanidine groups.

Biaryl derived amide modulators of vanilloid VR1 receptor

The invention is directed to novel vanilloid receptor type 1 (VR1) ligands. More specifically, the invention relates to novel biaryl-derived amides that are potent antagonists or agonists of VR1. Pharmaceutical and veterinary compositions and methods of treating mild to severe pain and various diseases using compounds of the invention are also described.