107575-59-7

Basic information

• Product Name: ETHYL PYRUVATE-3-FORMYLAMINO-4-METHOXYPHENYLHYDRAZONE
• Synonyms: ETHYL PYRUVATE-3-FORMYLAMINO-4-METHOXYPHENYLHYDRAZONE;2-[2-[3-(ForMylaMino)-4-Methoxyphenyl]hydrazinylidene]propanoic Acid Ethyl Ester
• CAS NO: 107575-59-7
• Molecular Formula: C₁₃H₁₇N₃O₄
• Molecular Weight: 279.29178
• Product Categories: Aromatics Compounds;Aromatics
• Mol File: 107575-59-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: Refrigerator
• Solubility: DMSO
• CAS DataBase Reference: ETHYL PYRUVATE-3-FORMYLAMINO-4-METHOXYPHENYLHYDRAZONE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL PYRUVATE-3-FORMYLAMINO-4-METHOXYPHENYLHYDRAZONE(107575-59-7)
• EPA Substance Registry System: ETHYL PYRUVATE-3-FORMYLAMINO-4-METHOXYPHENYLHYDRAZONE(107575-59-7)

Safety Data

• Hazardous Substances Data: 107575-59-7(Hazardous Substances Data)

Usage

Chemical Properties

Off-White Solid

Uses

Ethyl Pyruvate-3-formylamino-4-methoxyphenylhydrazone (cas# 107575-59-7) is a compound useful in organic synthesis.

Upstream product

• 609-14-3 2-acetylpropanoic acid ethyl ester 
• 149686-06-6 N-(2-methoxyl-5-nitrophenyl)formamide 
• 99-59-2 3-amino-4-methoxynitrobenzene 
• 78939-34-1 N-(5-amino-2-methoxylphenyl)formamide 

Downstream Products

• 119825-27-3 6-(Formylamino)-5-methoxyindol-2-carbonsaeure-ethylester 
• 80721-47-7 4,5-Dihydro-4,5-dioxo-1H-pyrrolo<2,3-f>chinolin-2,7,9-tricarbonsaeure-(2-ethyl)(7,9-dimethyl)ester 
• 72909-34-3 pyrroloquinoline quinone 
• 107575-60-0 6-amino-5-methoxy-2-ethoxycarbonylindole 
• 133706-80-6 5-Methoxy-1H-pyrrolo<2,3-f>chinolin-2,7,9-tricarbonsaeure-(2-ethyl)(7,9-dimethyl)ester 

Relevant articles and documents

Decarboxylated Methoxatin Analogues. Synthesis of 7- and 9-Decarboxymethoxatin

A total synthesis of two monodecarboxylated analogues of methoxatin (1) is described.The synthesis of 9-decarboxymethoxatin (4) was achieved starting with 8-hydroxyquinoline, constructing an appropriately substituted quinolylhydrazone of ethyl pyruvate with a Japp-Klingemann reaction and annulating the remaining pyrrole ring through a Fischer indole synthesis.The synthesis of 7-decarboxymethoxatin (3) first necessitated the construction of an appropriate indole from which the remaining pyridine ring could be annulated via a Doebner reaction.

SYNTHESIS OF PYRROLOQUINOLINE QUINONE (PQQ)

The invention relates to a novel nine step process for synthesizing PQQ (methoxatin). This process is efficient and reliably provides PQQ in excellent purity and high yield.