1076192-92-1

Basic information

• Product Name: L-erythro-Ritalinic Acid
• Synonyms: L-erythro-Ritalinic Acid;(αR,2S)-α-Phenyl-2-piperidineacetic Acid
• CAS NO: 1076192-92-1
• Molecular Formula: C13H17NO2
• Molecular Weight: 219.27958
• Product Categories: Aromatics;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 1076192-92-1.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: L-erythro-Ritalinic Acid(CAS DataBase Reference)
• NIST Chemistry Reference: L-erythro-Ritalinic Acid(1076192-92-1)
• EPA Substance Registry System: L-erythro-Ritalinic Acid(1076192-92-1)

Safety Data

• Hazardous Substances Data: 1076192-92-1(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 1076192-92-1 differently. You can refer to the following data:
1. L-erythro-Ritalinic Acid is used to create enantioselective stationary phases.
2. L-erythro-Ritalinic Acid is a single enantiomer of erythro Ritalinic acid (R533100).
3. A single enantiomer of erythro Ritalinic acid (R533100).

Upstream product

• 19395-39-2 dl-erythro-α-phenyl-α-(2-piperidyl)acetamide 
• 40572-71-2 threo-(-)-Methylphenidate 
• 298-59-9 methylphenidate hydrochloride 
• 129389-68-0 l-ritalinic acid 
• 2700-22-3 Benzylidenemalononitrile 
• 618-42-8 1-piperidin-1-yl-ethanone 
• 5005-36-7 phenyl-pyridin-2-yl-acetonitrile 
• 7251-52-7 2-phenyl-2-(pyridin-2-yl)acetamide 
• 19395-39-2 (±)-erythro/threo-2-phenyl-2-(piperidin-2-yl)acetamide 

Downstream Products

• 64407-57-4 N,N-dicyclohexylurea 
• 1382859-13-3 d-threo-ritalinic acid hydrochloride 
• 741705-70-4 d-threo-ritalinic acid hydrochloride 
• 19262-68-1 dexmethylphenidate hydrochloride 
• 851895-37-9 l-threo-ritalinic acid hydrochloride 

Relevant articles and documents

Preparation and structural analysis of (±)-threo-ritalinic acid

Hydrolysis of the methyl ester (±)-threo-methyl phenidate afforded the free acid in 40% yield, viz. (±)-threo-ritalinic acid, C 13H17NO2. Hydrolysis and subsequent crystallization were accomplished at pH values between 5 a

Microtubing-Reactor-Assisted Aliphatic C?H Functionalization with HCl as a Hydrogen-Atom-Transfer Catalyst Precursor in Conjunction with an Organic Photoredox Catalyst

Chlorine radical, which is classically generated by the homolysis of Cl2 under UV irradiation, can abstract a hydrogen atom from an unactivated C(sp3)?H bond. We herein demonstrate the use of HCl as an effective hydrogen-atom-transfer catalyst precursor activated by an organic acridinium photoredox catalyst under visible-light irradiation for C?H alkylation and allylation. The key to success relied on the utilization of microtubing reactors to maintain the volatile HCl catalyst. This photomediated chlorine-based C?H activation protocol is effective for a variety of unactivated C(sp3)?H bond patterns, even with primary C(sp3)?H bonds, as in ethane. The merit of this strategy is illustrated by rapid access to several pharmaceutical drugs from abundant unfunctionalized alkane feedstocks.

PROCESS FOR PREPARING METHYL PHENIDATE HYDROCHLORIDE

Disclosed herein is a process for the preparation of methyl phenidate hydrochloride (Formula I), comprising the steps of; hydrolyzing α-phenyl-α-pipyridyl acetamide (Formula II) in presence of mineral acid at reflux temperature and subsequent neutralization to yield threo -α-phenyl-α-pipyridyl-2-acetic acid (Formula III) which in presence of acidic catalyst reacts with methanol followed by treatment with alcoholic hydrochloride solution produces methyl phenidate hydrochloride.