107939-51-5

Upstream product

• 67-56-1 methanol 
• 7218-49-7 4-phenyl-3-butynoic acid 
• 3757-88-8 tributylstannylethynylbenzene 
• 96-32-2 bromoacetic acid methyl ester 
• 10229-11-5 4-phenyl-but-3-yn-1-ol 
• 6832-16-2 methyl diazoacetate 
• 536-74-3 phenylacetylene 
• 1360733-32-9 methyl 4-oxo-1-phenylbut-2-yn-1-yl carbonate 
• 124-41-4 sodium methylate 
• 187796-59-4 (E)-1-Chloro-4-phenyl-1-phenylsulfonylbut-1-en-3-yne 

Downstream Products

• 319919-30-7 2-diazo-4-phenyl-but-3-ynoic acid methyl ester 
• 1379002-12-6 methyl 7-((tert-butyldimethylsilyl)oxy)-2-(phenylethynyl)hept-2-enoate 

Relevant academic research and scientific papers

Regio- and stereoselective vinylic substitution reactions of α-haloenyne sulfones

The nucleophilic vinylic substitution reaction of (E)-α-haloenyne sulfones 2, 5-8 with sodium alkoxides proceeded regioselectively to give (E)-α-alkoxyenyne sulfones 9-17 in high yields with exclusive retention of their configuration.

Enantioselective Phosphine-Catalyzed Trimerization of γ-Aryl-3-butynoates via Isomerization/[3 + 2] Cyclization/Michael Addition Cascade

We disclose an l-isoleucine-derived amide phosphine-catalyzed trimerization of γ-aryl-3-butynoates, which undergo an isomerization to allenoate, [3 + 2] cyclization, and Michael addition cascade. Exocyclopentene derivatives bearing an all-carbon quaternar

Tandem Regioselective Hydroformylation-Hydrogenation of Internal Alkynes Using a Supramolecular Catalyst

New supramolecular ligands containing an acyl guanidine function were designed based on the strategy of increasing the π-acceptor ability of phosphine ligands by introducing electron-withdrawing groups. By applying this novel catalytic system, a general protocol for the Rh-catalysed hydroformylation-hydrogenation of unsymmetrical internal alkynes, functionalized with a carboxylic acid, was found to furnish aliphatic aldehydes in high regio- and chemoselectivities. Control experiments confirm the enzyme-like supramolecular catalyst mode of action.

N -heterocyclic carbene-catalyzed internal redox reaction of alkynals: An efficient synthesis of allenoates

An efficient N-heterocyclic carbene (NHC)-catalyzed internal redox reaction of alkynals that bear a γ leaving group has been developed. This process provides a new access to a range of allenoates in good yields. Preliminary results demonstrate that the en

Alkynylation of α-halocarbonyl compounds - A Stille-type cross-coupling for the formation of C(sp)-C(sp3) bonds under neutral conditions

A direct alkynylation of readily available α-halo esters and amides with high yields is described herein; a distinct switch from diyne formation to alkynylation products was attained under neutral conditions. The Royal Society of Chemistry.

Asymmetric synthesis of 1-alkynylcyclopropane-1-carboxylates

Dirhodium tetrakis(S-(N-dodecylbenzenesulfonyl)prolinate) (Rh2S-DOSP4) catalyzed decomposition of methyl alkynyldiazoacetates in the presence of alkenes results in highly diastereoselective and enantioselective cyclopropanations. (C) 2000 Published by Elsevier Science Ltd.