107967-87-3

Upstream product

• 111-25-1 1-bromo-hexane 
• 87228-66-8 1-Methyl-4-(1-methylsulfanyl-2-phenyl-ethanesulfonyl)-benzene 
• 87228-73-7 β-methylthio-β-(p-tolylsulfonyl)styrene 
• 100-52-7 benzaldehyde 
• 59662-65-6 methylthiomethyl p-tolyl sulfone 

Downstream Products

• 6683-96-1 2-Octanone, 1-phenyl- 

Relevant academic research and scientific papers

Reduction of Ketene Dithioacetal S,S-Dioxides with Sodium Borohydride and Its Application to a Convenient Synthesis of Alkyl Arylmethyl Ketones

The C-C double bond of a ketene dithioacetal S,S-dioxide was found to undergo reduction with sodium borohydride.This fact provides an efficient synthetic route from an aromatic aldehyde to an alkyl arylmethyl ketone using methylthiomethyl p-totyl sulfone.

ALDEHYDE AND KETONE SYNTHESES USING METHYLTHIOMETHYL p-TOLYL SULFONE

Methylthiomethyl p-tolyl sulfone (1) was conveniently alkylated to give mono- and dialkylated products (2 and 4).Reaction conditions for the transformation of 2 and 4 into aldehydes (3) and ketones (5), respectively, were exploited.