87228-66-8Relevant academic research and scientific papers
Carbon-Carbon Bond Formation with New Mitsunobu Reagents
Tsunoda, Tetsuto,Nagaku, Miwa,Nagino, Chisato,Kawamura, Yumi,Ozaki, Fumie,et al.
, p. 2531 - 2534 (2007/10/02)
The efficiency of three azodicarboxylic acid derivatives and a stabilized phosphorane in the Mitsunobu type C-C bond formation was compared utilizing the reactions of three nucleophiles of different pKa's and several alcohols of different structure types.The study established the characteristics of each reagent.The synthesis of two insect pheromone analogs was accomplished effectively using these homologation reactions.
Synthesis of homoallylic sulphides and selenides by Lewis acid mediated displacement reactions of sulphones
Simpkins, Nigel S.
, p. 323 - 332 (2007/10/02)
A number of α-seleno- and α-thio-substituted sulphones have been prepared, and subsequently reacted with allyltrimethylsilane, using EtAlCl2 as Lewis acid, to give homoallylic selenides or sulphides respectively. Some unsaturated substrates und
SYNTHESIS OF ALLYLIC SULPHIDES AND SELENIDES BY LEWIS ACID MEDIATED DISPLACEMENT REACTIONS OF SULPHONES
Simpkins, Nigel S.
, p. 6787 - 6790 (2007/10/02)
Allylic sulphides or selenides are produced by reaction of appropriate α-sulphonyl sulphides or selenides with allyltrimethylsilane in the presence of EtAlCl2.
Reduction of Ketene Dithioacetal S,S-Dioxides with Sodium Borohydride and Its Application to a Convenient Synthesis of Alkyl Arylmethyl Ketones
Ogura, Katsuyuki,Ohtsuki, Kazuo,Takahashi, Kazumasa,Iida, Hirotada
, p. 1597 - 1598 (2007/10/02)
The C-C double bond of a ketene dithioacetal S,S-dioxide was found to undergo reduction with sodium borohydride.This fact provides an efficient synthetic route from an aromatic aldehyde to an alkyl arylmethyl ketone using methylthiomethyl p-totyl sulfone.
A VERSATILE REAGENT FOR SYNTHESIS OF α-HYDROXY ALDEHYDES AND KETONES --- METHYLTHIOMETHYL p-TOLYL SULFONE
Ogura, Katsuyuki,Tsuruda, Toshihiko,Takahashi, Kazumasa,Iida, Hirotada
, p. 3665 - 3668 (2007/10/02)
Methylthiomethyl p-tolyl sulfone (1) can be utilized for synthesizing α-hydroxy ketones as well as α-hydroxy aldehydes, the hydroxyl group of which is protected with acetyl, tetrahydropyranyl, or methoxymethyl group.
UTILIZATION OF METHYLTHIOMETHYL p-TOLYL SULFONE IN ORGANIC SYNTHESIS
Ogura, Katsuyuki,Yahata, Nobuhiro,Hashizume, Kimitoshi,Tsuyama, Koichi,Takahashi, Kazumasa,Iida, Hirotada
, p. 767 - 770 (2007/10/02)
Methylthiomethyl p-tolyl sulfone was found to be one of the useful reagents for preparation of various organic compounds such as S-methyl α-ketocarbothioates, carboxylic esters, five- and six-membered cycloalkanones, and α-methoxy-α-arylacetic esters.
