107982-60-5

Upstream product

• 89278-33-1 cyclo-<(2(S)-Amino-10-chloro-8(S),9(R)-O-isopropylidenedecanoyl)-dimethylglycyl-(S)-phenylalanyl-(R)-prolyl> 
• 108071-97-2 (S)-2-Benzyloxycarbonylamino-7-((4S,5S)-5-chloromethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-heptanoic acid methyl ester 
• 89278-32-0 (S)-2-Benzyloxycarbonylamino-7-((4S,5R)-5-chloromethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-heptanoic acid 
• 108071-97-2 Methyl 2(S)-benzyloxycarbonylamino-10-chloro-8(S),9(R)-O-isopropylidenedecanoate 
• 89278-31-9 Methyl 10-Benzyloxy-2-(S)-benzyloxycarbonylamino-8(S),9(S)-O-isopropylidene-2(E/Z),6(E/Z)-decadienoate 
• 88568-96-1 Methyl N-(dimethylglycyl)-(S)-phenylalanyl-(R)-prolinate 
• 89321-01-7 Pentafluorophenyl N-<2(S)-benzyloxycarbonylamino-10-chloro-8(S),9(R)-O-isopropylidenedecanoyl>-dimethylglycyl-(S)-phenylalanyl-(R)-prolinate 
• 108071-98-3 Methyl of N-<2(S)-benzyloxycarbonylamino-10-chloro-8(S),9(R)-O-isopropylidenedecanoyl>-dimethylglycyl-(S)-phenylalanyl-(R)-prolinate 
• 108071-96-1 Methyl 2(S)-benzyloxycarbonylamino-10-hydroxy-8(S),9(S)-O-isopropylidenedecanoate 
• 89278-30-8 (E/Z)-8-Benzyloxy-6(S),7(S)-O-isopropylidene-4-octenal 
• 89278-34-2 8-Benzyloxy-6(S),7(S)-O-isopropylidene-1-octanal 
• 108072-00-0 cyclo<(2(γ)-Amino-10-chloro-8(S),9(R)-dihydroxydecanoyl)-dimethylglycyl-(S)-phenylalanyl-(R)-prolyl> 
• 89760-52-1 cyclo-(L-Ade-Aib-L-Phe-D-Pro) 
• 88568-96-1 H-Aib-L-Phe-D-Pro-OMe 

Downstream Products

• 53342-16-8 chlamydocin 
• 88643-73-6 chlamydocin 
• 88643-73-6 epi-chlamydocin 

Relevant academic research and scientific papers

Amino Acids and Peptides; 55. Synthesis of Biologically Active Cyclopeptides; 7. Total Synthesis of Chlamydocin

Methods for the synthesis of cyclopeptides containing non-essential amino acids are described.The total synthesis of the highly cancerostatic Chlamydocin is published.

Synthesis of the cytostatic cyclic tetrapeptide, chlamydocin

Chlamydocin has been synthesized by a route utilizing allylic hydroxylation and epoxidation of the DL-2-amino-9-decenoic acid residue to form the 2-amino-8-oxo-9,10-epoxydecanoic acid residue.