108227-95-8

Basic information

• Product Name: 2-acetamido-5⁽⁶⁾-benzoylbenzimidazole
• CAS NO: 108227-95-8
• Molecular Weight: 279.298
• Mol File: 108227-95-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-acetamido-5⁽⁶⁾-benzoylbenzimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-acetamido-5⁽⁶⁾-benzoylbenzimidazole(108227-95-8)
• EPA Substance Registry System: 2-acetamido-5⁽⁶⁾-benzoylbenzimidazole(108227-95-8)

Safety Data

• Hazardous Substances Data: 108227-95-8(Hazardous Substances Data)

Upstream product

• 52329-60-9 (2-amino-1H-benzimidazol-5-yl)(phenyl)methanone 
• 108-24-7 acetic anhydride 
• 75-36-5 acetyl chloride 
• 31431-39-7 mebendazole 
• 39070-63-8 4-benzoylbenzene-1,2-diamine 
• 57070-71-0 (3,4-diaminophenyl)phenylmethanone hydrochloride 

Downstream Products

• 75501-04-1 2-acetamido-5(6)-(α-hydroxy-α-phenylmethyl)benzimidazole 

Relevant articles and documents

Antiparasitic agents: Part XVII - Synthesis of 5-acyl-2-acylamino-1H-benzimidazoles and their macrofilaricidal and chemosterilizing activities

5-Acyl-2-acylamino-1H-benzimidazoles (3a-w) have been synthesized and evaluated for their macrofilaricidal and chemosterilizing activities in experimental animals.Compounds 3a,b,q exhibit high order of adulticidal activity against L. carinii (cotton rats) and A. viteae (Mastomys) infections while compounds 3b,o q show marked chemosterilizing effect on adult female filariids.

Synthesis of the mebendazol metabolite 2-amino-benzoyl-benzimidazole

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