108679-71-6

Basic information

• Product Name: 3-AMINO-2-CHLOROBENZOIC ACID
• Synonyms: 3-AMINO-2-CHLOROBENZOIC ACID;2-Chloro-3-aminobenzoic acid;Benzoic acid,3-aMino-2-chloro-
• CAS NO: 108679-71-6
• Molecular Formula: C₇H₆ClNO₂
• Molecular Weight: 171.58
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Carboxylic Acids;Phenyls & Phenyl-Het;Aromatic Amino Acids;Peptide Synthesis;Unnatural Amino Acid Derivatives
• Mol File: 108679-71-6.mol
• Article Data: 5

Chemical Properties

• Melting Point: 154-160 °C(lit.)
• Boiling Point: 346.532 °C at 760 mmHg
• Flash Point: 163.377 °C
• Appearance: /
• Density: 1.477 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.649
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 3.19±0.25(Predicted)
• CAS DataBase Reference: 3-AMINO-2-CHLOROBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-2-CHLOROBENZOIC ACID(108679-71-6)
• EPA Substance Registry System: 3-AMINO-2-CHLOROBENZOIC ACID(108679-71-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 108679-71-6(Hazardous Substances Data)

Usage

General Description

3-AMINO-2-CHLOROBENZOIC ACID is a chemical compound with the molecular formula C7H6ClNO2. It belongs to the class of benzoic acid derivatives and contains both an amino group and a chlorine atom. 3-AMINO-2-CHLOROBENZOIC ACID is commonly used in organic synthesis as a building block for the preparation of various pharmaceuticals, dyes, and agrochemicals. It can also be used in the production of polymers and as a reagent in chemical reactions. 3-AMINO-2-CHLOROBENZOIC ACID has potential applications in the pharmaceutical industry due to its structural properties and functional groups.

InChI:InChI=1/C7H6ClNO2/c8-6-4(7(10)11)2-1-3-5(6)9/h1-3H,9H2,(H,10,11)

Upstream product

• 3970-35-2 2-chloro-3-nitrobezoic acid 
• 3970-40-9 2-chloro-3-nitrotoluene 
• 249289-91-6 3-acetylamino-2-chloro-benzoic acid 

Downstream Products

• 302945-33-1 2-chloro-3-(8-methoxycarbonyloxy-2,4-dioxo-4H-benzo[e][1,3]oxazin-3-yl)-benzoic acid 
• 528607-70-7 C₂₀H₁₉ClN₂O₃S 
• 528607-66-1 methyl 2-chloro-3-(3-cyano-4-isobutyloxybenzoylamino)benzoate 

Relevant articles and documents

Development of nematic and orthogonal smectic phases in short-core fluorinated hockey-stick shaped liquid crystal compounds

Here we report synthesis and investigations on novel short-core hockey-stick shaped molecules bearing a 4-n-alkyloxy-2-hydroxybenzylidene moiety at one end and polar fluoro-biphenyl moiety at the other end. The polar chloro and fluoro substituent at the lateral position of the core confers nematic and orthogonal smectic mesomorphism. The mesophase morphology is characterized by polarizing optical microscopy (POM), differential scanning calorimetry (DSC), X-ray diffraction (XRD), electro-optical study and dielectric spectroscopy. The fluorinated compounds 1b (n = 16) and 1c (n = 18) have long terminal hydrocarbon tail and show orthogonal smectic phases with antiferroelectric switching behaviour. The chlorinated compound 2e (n = 8) with relatively short terminal chain length exhibits only a monotropic nematic phase on cooling. The nematic phase is comprised of cybotactic clusters as confirmed by XRD and exhibits electro-optic switching. The compound 2i (n = 12) manifests a short range enantiotropic nematic and additional orthogonal smectic phase. Dielectric spectroscopy reveals polar correlations in the nematic and smectic phases.

SUBSTITUTED QUINOLINES AND METHODS FOR TREATING CANCER

Substituted quinoline compounds, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds to treat, prevent or ameliorate cancer are provided.

A new family of four-ring bent-core nematic liquid crystals with highly polar transverse and end groups

Non-symmetrically substituted four-ring achiral bent-core compounds with polar substituents, i.e.., chloro in the bent or transverse direction in the central core and cyano in the lateral direction at one terminal end of the molecule, are designed and syn