108783-68-2

Upstream product

• 7377-26-6 4-Methoxycarbonylbenzoyl chloride 
• 1011-51-4 5-(4-methoxyphenyl)-1,3-oxazole 
• 619-44-3 methyl 4-iodobenzoate 
• 3883-94-1 2-amino-4'-methoxyacetophenone hydrochloride 
• 108783-61-5 N-[2-(4-Methoxy-phenyl)-2-oxo-ethyl]-terephthalamic acid methyl ester 

Downstream Products

• 108783-81-9 Acid Chloride of 2-(4-Carboxyphenyl)-5-(4-methoxyphenyl)oxazole 
• 108783-87-5 2-(4-Carbamidophenyl)-5-(4-methoxyphenyl)oxazole 
• 108783-75-1 4-(5-(4-methoxyphenyl)oxazole-2-yl)benzoic acid 

Relevant academic research and scientific papers

Synthesis of 2,5-diaryloxazoles through van Leusen reaction and copper-mediated direct arylation

The direct arylation of 5-aryloxazoles, prepared by the van Leusen reaction, with various aryl iodides is effectively promoted by a system of CuI combined with PPh3 and Na2CO3 as a ligand and a base, respectively, in DMF to produce the corresponding 2,5-diaryloxazoles in good yields.

SYNTHESIS AND SPECTRAL AND LUMINESCENT PROPERTIES OF 4-(5-ARYLOXAZOYL-2)BENZOIC ACIDS AND THEIR DERIVATIVES

Condensation of acid chloride of monomethyl terephtalate with ω-aminomethylarylketones and subsequent cyclodehydration of the resulting amides in sulfuric acid or phosphorus oxychloride give rise to methyl 4-(5-aryloxazolyl-2)benzoates which led to the co