108783-68-2Relevant articles and documents
Synthesis of 2,5-diaryloxazoles through van Leusen reaction and copper-mediated direct arylation
Yoshizumi, Tomoki,Satoh, Tetsuya,Hirano, Koji,Matsuo, Daisuke,Orita, Akihiro,Otera, Junzo,Miura, Masahiro
experimental part, p. 3273 - 3276 (2009/08/09)
The direct arylation of 5-aryloxazoles, prepared by the van Leusen reaction, with various aryl iodides is effectively promoted by a system of CuI combined with PPh3 and Na2CO3 as a ligand and a base, respectively, in DMF to produce the corresponding 2,5-diaryloxazoles in good yields.