108850-91-5Relevant articles and documents
Utility of 2-hydrazino-4,6-dimethylpyridine in heterocyclic synthesis
Al-Ashmawy,Abd El-Samii,El Feky,Osman
, p. 110 - 114 (2007/10/03)
2-Hydrazino-4,6-dimethylpyrimidine (1) readily underwent ring closure with benzoyl chloride to give 5,7-dimethyl-3 phenyl- 1,2,4-triazolo[4,3-a]pyrimidine (4a). Either N-benzoyl derivative (2) or the hydrazone (3a) can be used for formation of compound 4a. Reaction of compound 1 with acetylacetone gave the pyrazole derivative (6) rather than 1,2,4-triazepine derivative (5). The pyrrole (9) was the sole product from cyclization of 1 with 2,5 hexanedione. Reaction of compound 1 with carbon disulphide or ethyl chloroformate gave 1,2,4-triazolo[4,3-a]pyrimidines (10 and 12). The reaction of thiosemicarbazides (13 a-c) with ethyl bromoacetate and DCCD was investigated.