108908-70-9

Basic information

• Product Name: (3S,4R)-cis-1-(p-anisyl)-3-phenoxy-4-styrylazetidin-2-one
• CAS NO: 108908-70-9
• Molecular Weight: 371.436
• Mol File: 108908-70-9.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: (3S,4R)-cis-1-(p-anisyl)-3-phenoxy-4-styrylazetidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,4R)-cis-1-(p-anisyl)-3-phenoxy-4-styrylazetidin-2-one(108908-70-9)
• EPA Substance Registry System: (3S,4R)-cis-1-(p-anisyl)-3-phenoxy-4-styrylazetidin-2-one(108908-70-9)

Safety Data

• Hazardous Substances Data: 108908-70-9(Hazardous Substances Data)

Upstream product

• 15286-52-9 N-(4-Methoxyphenyl)-3-phenylpropenaldimine 
• 701-99-5 Phenoxyacetyl chloride 
• 104-94-9 4-methoxy-aniline 
• 14371-10-9 (E)-3-phenylpropenal 
• 104-55-2 3-phenyl-propenal 
• 80542-40-1 N-cinnamylidene-p-anisidine 
• 88315-63-3 (E)-4-methoxy-N-((E)-3-phenylallylidene)aniline 
• 122-59-8 2-phenoxyacetic acid 
• 123525-44-0 N-(3-phenyl-2-propenylidene)-4-methoxyaniline 
• 22835-33-2 (4-Methoxy-phenyl)-[(E)-3-phenyl-prop-2-en-(E)-ylidene]-amine 
• 114476-97-0 phenoxythioacetic acid S-benzothiazol-2-yl ester 
• 132377-49-2 (E)-(2R,3S)-3-(4-Methoxy-phenylamino)-2-phenoxy-5-phenyl-pent-4-enoic acid 

Downstream Products

• 133504-98-0 (3S,4R)-1-(4-Methoxy-phenyl)-4-{[(E)-4-methoxy-phenylimino]-methyl}-3-phenoxy-azetidin-2-one 
• 136137-18-3 1-p-methoxyphenyl-3-phenoxy-4-(1'-p-methoxyphenyl-3'-phenoxyazetidin-2'-one-4'-yl)-azetidin-2-one 
• 136137-18-3 (2R,3S,2'R,3'S)-1,1'-Bis-(4-methoxy-phenyl)-3,3'-diphenoxy-[2,2']biazetidinyl-4,4'-dione 
• 133504-98-0 (3S,4R)-1-(4-Methoxy-phenyl)-4-{[(E)-4-methoxy-phenylimino]-methyl}-3-phenoxy-azetidin-2-one 
• 133505-04-1 (2S,3S)-1-(4-Methoxy-phenyl)-4-oxo-3-phenoxy-azetidine-2-carbaldehyde 
• 123525-47-3 3-phenoxy-4-(2'-phenylethenyl)-2-azetidinone 
• 133505-04-1 cis-4-formyl-1-(p-methoxyphenyl)-3-phenoxyazetidin-2-one 

Relevant articles and documents

An easy and convenient synthesis of β-lactams via a one-pot staudinger reaction with 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride starting from substituted carboxylic acids

An easy and convenient direct synthesis of 2-azetidinones is described. The [2+2] cycloaddition reaction of imines and carboxylic acids using 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride (DMTMM) has been employed to synthesize a variety of 2-azetidinones in high yields. The products were easily isolated because the byproducts are highly soluble in water.

2,2′-dibenzothiazolyl disulfide: A versatile reagent for the synthesis of 2-azetidinones

2,2′-Dibenzothiazolyl disulfide has been found to be a versatile reagent that provides a convenient and efficient route for the synthesis of β-lactams from Schiffs bases and alkoxy/aryloxy acetic acids. The process involves the formation of thioester of the corresponding acid. Finally, condensation of titanium enolates, derived from these esters, with imines completes the synthesis of 2-azetidinones.

Triphosgene: A versatile reagent for the synthesis of azetidin-2-ones

An efficient use of triphosgene, as an acid activator, for the synthesis of substituted azetidin-2-ones via ketene-imine cycloaddition reaction using various acids and imines have been described.