123486-12-4Relevant academic research and scientific papers
Dihydropyrimidine Calcium Channel Blockers. 2. 3-Substituted-4-aryl-1,4-dihydro-6-methyl-5-pyrimidinecarboxylic Acid Esters as Potent Mimics of Dihydropyridines
Atwal, Karnail S.,Rovnyak, George C.,Kimball, S. David,Floyd, David M.,Moreland, Suzanne,et al.
, p. 2629 - 2635 (2007/10/02)
To enhance the intrinsic potency of dihydropyrimidine calcium channel blockers, we have modified the structure of previously described 2-heteroalkyl-1,4-dihydropyrimidines 2 to 3-substituted 1,4-dihydropyrimidines 3.Structure-activity studies using potass
3-oxo-1,2,4-triazolo(4,3-A) pyrimidine-6-carboxylic acid esters
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, (2008/06/13)
Compounds having the formula STR1 and pharmaceutically acceptable salts thereof, wherein R4 is aryl are disclosed. These novel compounds are useful, for example, as cardiovascular agents.
