108947-99-5Relevant academic research and scientific papers
Synthesis of 5-chloro-5,8-dideaza analogues of folic acid and aminopterin targeted for colon adenocarcinoma
Hynes,Kumar,Tomazic,Washtien
, p. 1515 - 1519 (2007/10/02)
Several classical quinazoline analogues of folic acid bearing chloro or methyl substituents at position 5 were evaluated as inhibitors of the growth of four human gastrointestinal adenocarcinoma cell lines in vitro. The preparation of two of these, 5-chlo
