109309-90-2

Basic information

• Product Name: Phenylalanine, N-benzoyl-, 1,1-dimethylethyl ester
• CAS NO: 109309-90-2
• Molecular Formula: C20H23NO3
• Molecular Weight: 325.408
• Mol File: 109309-90-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Phenylalanine, N-benzoyl-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phenylalanine, N-benzoyl-, 1,1-dimethylethyl ester(109309-90-2)
• EPA Substance Registry System: Phenylalanine, N-benzoyl-, 1,1-dimethylethyl ester(109309-90-2)

Safety Data

• Hazardous Substances Data: 109309-90-2(Hazardous Substances Data)

Upstream product

• 75898-42-9 (R,S)-tert-butyl 2-bromo-3-phenylpropionate 
• 106377-74-6 2-Azido-3-phenyl-propionsaeure-tert-butylester 
• 53-21-4 (-)-cocaine hydrochloride 
• 100-39-0 benzyl bromide 
• 98-88-4 benzoyl chloride 
• 23912-53-0 N-[2-Phenyl-1-(N'-phenyl-hydrazinocarbonyl)-ethyl]-benzamide 
• 1907-33-1 lithium tert-butoxide 
• 16367-71-8 t-butyl (RS)-phenylalaninate 
• 519-09-5 benzylecgonine 

Downstream Products

• 2566-22-5 DL-N-benzoylphenylalanine 

Relevant articles and documents

Solid-phase synthetic method for (±)-α-amino acids via phase-transfer catalytic alkylation

A solid supported glycineimine t-butyl ester was designed and successfully applied to the synthesis of (±)-α-amino acids. The phase-transfer catalytic alkylation, followed by acidic hydrolysis and benzoylation gave N-benzoyl-α-amino acid tert-butyl esters in high yields (up to 92%).

An oxidative transformation of N′-phenylhydrazide to t-butyl ester using a copper(II) halide-lithium t-butoxide system

Reactions of hydrazides or N1-phenylhydrazides with a copper(II) reagent prepared from copper(II) bromide and lithium t-butoxide smoothly proceeded to give the corresponding t-butyl ester in high yield.