109323-22-0Relevant academic research and scientific papers
Prostaglandins and Prostaglandin Intermediates. XVII - Synthesis of the Main Metabolite of the PGF2α Analogue Cloprostenol
Theil, Fritz,Costisella, Burkhard,Mahrwald, Rainer,Gross, Hans,Schick, Hans,Schwarz, Sigfrid
, p. 435 - 440 (2007/10/02)
The δ-lactone 5, the main metabolite of the PGF2α analogue cloprostenol, is prepared in four steps from the homologous γ-lactone 1 in an overall yield of 42 percent by conversion into the γ-lactol 3, which is olefinated with diethyl 1-cyano-1-d
