67039-86-5Relevant academic research and scientific papers
Prostaglandins and Prostaglandin Intermediates. XVII - Synthesis of the Main Metabolite of the PGF2α Analogue Cloprostenol
Theil, Fritz,Costisella, Burkhard,Mahrwald, Rainer,Gross, Hans,Schick, Hans,Schwarz, Sigfrid
, p. 435 - 440 (2007/10/02)
The δ-lactone 5, the main metabolite of the PGF2α analogue cloprostenol, is prepared in four steps from the homologous γ-lactone 1 in an overall yield of 42 percent by conversion into the γ-lactol 3, which is olefinated with diethyl 1-cyano-1-d
Prostaglandin Analogues Possessing Antinidatory Effects. 2. Modification of the α Chain
Hayashi, Masaki,Arai, Yoshinobu,Wakatsuka, Hirohisa,Kawamura, Masanori,Konishi, Yoshitaka,et al.
, p. 525 - 535 (2007/10/02)
Additional double bonds were introduced into the α chain in 16-phenoxy-, 16-(3-chlorophenoxy)-, 16--, and 16-(4-chlorophenoxy)-17,18,19,20-tetranorprostaglandins which have antinidatory effects.Of these analogues, the Δ3/
