109448-23-9Relevant academic research and scientific papers
Iodine-Promoted C(sp 2)-H thiolation of maleimides with dimethyl sulfoxide and thiols
Tan, Hong-Ru,Wang, Lun,Yang, Zhen-Hua,Zhao, Sheng-Yin,Zhu, Jia-Nan
, p. 4113 - 4123 (2018/10/15)
Iodine-promoted C(sp 2)-H methylthiolation of maleimides using DMSO as synthon has been developed to afford 3-methylthiomaleimides in moderate yields under metal-free conditions. In addition, 3-thiomaleimides were synthesized from maleimides an
Copper-catalyzed intermolecular thioamination of maleimides with thiols and formamides: A one-step construction of 3-Amino-4-Thiomaleimides using formamides as nitrogen sources
Yang, Zhen-Hua,Zhu, Jia-Nan,Jin, Ze-Hui,Zheng, Jian,Zhao, Sheng-Yin
, p. 4627 - 4636 (2019/02/01)
A highly efficient copper-catalyzed intermolecular C(sp2)-H thioamination of maleimides with thiols and formamides in the presence of fluoroboric acid is reported using various readily available formamides as nitrogen sources and solvents. A diverse range of 3-Amino-4-Thiomaleimides is obtained with good yields under mild conditions, involving C-N and C-S bond formation. This methodology enriches current C-N and C-S bond formation chemistry and features operational simplicity and excellent functional-group tolerance.
Three-Component Coupling Reactions of Maleimides, Thiols, and Amines: One-Step Construction of 3,4-Heteroatom-functionalized Maleimides by Copper-Catalyzed C(sp2)?H Thioamination
Yang, Zhen-Hua,Tan, Hong-Ru,An, Yu-Long,Zhao, Yu-Wei,Lin, Hao-Peng,Zhao, Sheng-Yin
supporting information, p. 173 - 179 (2017/11/22)
A copper-catalyzed intermolecular thioamination of maleimides with thiols and amines has been developed. A diverse range of 3-amino-4-thiomaleimides and 3,4-dihydropyrrolo[3,4-b][1,4]thiazine-5,7(2H,6H)-diones were obtained with good yields, involving C?N and C?S bond formations. This methodology is very practical and features high atom economy, excellent functional group tolerance. (Figure presented.).
