109632-73-7Relevant academic research and scientific papers
Synthesis, biological evaluation and chemometric analysis of indazole derivatives. 1,2-Disubstituted 5-nitroindazolinones, new prototypes of antichagasic drug
Vega, María Celeste,Rolón, Miriam,Montero-Torres, Alina,Fonseca-Berzal, Cristina,Escario, José Antonio,Gómez-Barrio, Alicia,Gálvez, Jorge,Marrero-Ponce, Yovani,Arán, Vicente J.
supporting information, p. 214 - 227 (2013/02/23)
Chagas disease chemotherapy, currently based on only two drugs, nifurtimox and benznidazole, is far from satisfactory and therefore the development of new antichagasic compounds remains an important goal. On the basis of antichagasic properties previously
Selective synthesis of 2-substituted indazolin-3-ones without N-1 protection
Arán, Vicente J.,Díez-Barra, Enrique,De La Hoz, Antonio,Sánchez-Verdú, Prado
, p. 129 - 136 (2007/10/03)
N-2-Alkylation of indazolin-3-ones was performed in neutral conditions. This method represents a direct and efficient entry to a class of compounds having interesting biological activities, avoiding the generally required N-1 protection.
ON THE ISOMERIZATION OF DIALKYL INDAZOLONES TO DIHYDRO-QUINAZOLINONES
Baiocchi, Leandro,Picconi, Giuseppe
, p. 5255 - 5256 (2007/10/02)
1,2-dialkyl-3-indazolones isomerize in basic medium to dihydro-4-quinazolinones.These latter, under more drastic conditions, undergo dismutation to 4(3H)-quinazolinones and antranilamides.
