109741-16-4

Upstream product

• 17642-90-9 1-benzylhexahydro-2H-azepine-2-thione 
• 5815-08-7 tert-Butoxybis(dimethylamino)methane 

Downstream Products

• 109741-21-1 (E)-4-(1-benzyl-2-dimethoxymethylpiperidin-2-yl)-3-buten-2-one 
• 109741-20-0 1-benzyl-2-dimethoxymethylpiperidine-2-carbaldehyde 
• 109741-18-6 1-benzyl-4,5,6,7-tetrahydro-1H-azepine-3-carbaldehyde 
• 77204-60-5 1-benzyl-1-azaspiro<5.5>undec-7-en-9-one 
• 109741-17-5 1-benzyl-2-methylthio-4,5,6,7-tetrahydro-1H-azepine-3-carbaldehyde 

Relevant academic research and scientific papers

New Piperidinic Synthons via Ring Contraction. Formal Synthesis of (+/-)-Perhydrohistrionicotoxin

The 2,2-bifunctionalized piperidines 6 and 10 were obtained via ring contraction of the seven-membered heterocyclic enamino aldehyde 5 in nearly quantitative yield.The synthesis of 1-benzyl-1-azaspiroundec-7-en-9-one 9 (a formal precursor or perhydrohistrionicotoxin 1b) in 3 steps from the piperidinedialdehyde monoacetal 6, is reported.