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109882-25-9

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109882-25-9 Usage

Uses

Impurity of Bendamustine (B132500), an anticancer drug.

Check Digit Verification of cas no

The CAS Registry Mumber 109882-25-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,9,8,8 and 2 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 109882-25:
(8*1)+(7*0)+(6*9)+(5*8)+(4*8)+(3*2)+(2*2)+(1*5)=149
149 % 10 = 9
So 109882-25-9 is a valid CAS Registry Number.

109882-25-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name Methyl 4-{5-[bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazol-2- yl}butanoate

1.2 Other means of identification

Product number -
Other names Methylhydroxy-Celecoxib

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:109882-25-9 SDS

109882-25-9Downstream Products

109882-25-9Relevant articles and documents

Improved continuous flow processing: Benzimidazole ring formation via catalytic hydrogenation of an aromatic nitro compound

Chen, Jian,Przyuski, Katrin,Roemmele, Renee,Bakale, Roger P.

, p. 1427 - 1433 (2014)

In the development of a new route to bendamustine hydrochloride, the API in Treanda, the key benzimidazole intermediate 5 was generated via catalytic heterogeneous hydrogenation of an aromatic nitro compound using a batch reactor. Because of safety concer

Process for the preparation of bendamustine hydrochloride and related compounds

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Paragraph 0146; 0147; 0148; 0149; 0150, (2013/07/25)

The present invention relates to a process for preparing bendamustine hydrochloride, derivatives and related compounds thereof.

PROCESSES FOR THE PREPARATION OF BENDAMUSTINE

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Page/Page column 19-20, (2010/04/28)

New methods for the preparation of bendamustine, and the pharmaceutical salts thereof, are described. Novel compounds useful for the preparation of bendamustine are also described.

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