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1-(4-methoxyphenyl)-2-phenylquinazolin-4(1H)-one is a complex organic compound belonging to the quinazolinone class, characterized by a quinazolinone core with a 4-methoxyphenyl group at position 1 and a phenyl group at position 2. This molecule is known for its potential pharmacological properties, particularly as a kinase inhibitor, which can be useful in the development of anticancer and antiviral drugs. The presence of the methoxy group on the phenyl ring contributes to its lipophilicity, potentially enhancing its ability to cross cell membranes. The compound's structure and properties make it a subject of interest in medicinal chemistry for the design of novel therapeutic agents.

1099-99-6

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1099-99-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1099-99-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,9 and 9 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1099-99:
(6*1)+(5*0)+(4*9)+(3*9)+(2*9)+(1*9)=96
96 % 10 = 6
So 1099-99-6 is a valid CAS Registry Number.

1099-99-6Downstream Products

1099-99-6Relevant academic research and scientific papers

Synthesis of quinazolin-4(1 H)-ones via amination and annulation of amidines and benzamides

Hu, Fangpeng,Cui, Xinfeng,Ban, Zihui,Lu, Guoqiang,Luo, Nan,Huang, Guosheng

, p. 2356 - 2360 (2019)

Quinazolinones have broad applications in the biological, pharmaceutical and material fields. Studies on the synthesis of these compounds are therefore widely conducted. Herein, a novel and highly efficient copper-mediated tandem C(sp2)-H amination and annulation of benzamides and amidines for the synthesis of quinazolin-4(1H)-ones is proposed. This synthetic route can be useful for the construction of quinazolin-4(1H)-one frameworks.

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