1101167-59-2Relevant academic research and scientific papers
Preparation of functionalized organoindium reagents by means of magnesium insertion into organic halides in the presence of InCl3 at room temperature
Bernhardt, Sebastian,Shen, Zhi-Liang,Knochel, Paul
supporting information, p. 828 - 833 (2013/02/23)
Magnesium, indium, palladium: An efficient one-pot procedure for the direct preparation of triorganoindium reagents from organic halides by means of magnesium insertion in the presence of InCl3 and LiCl is reported (see scheme). The organoindium reagents are obtained in good yields from functionalized aryl, heteroaryl, and alkyl bromides and benzyl chlorides at 25 °C in THF within 4h. Moreover, the resulting organoindium reagents could be efficiently used as reagents in Pd-catalyzed cross-coupling reactions with a wide functional group tolerance. Copyright
Scope of the suzuki-Miyaura cross-coupling reactions of potassium heteroaryltrifluoroborates
Molander, Gary A.,Canturk, Belgin,Kennedy, Lauren E.
supporting information; experimental part, p. 973 - 980 (2009/07/11)
A wide variety of bench-stable potassium heteroaryltrifluoroborates were prepared, and general reaction conditions were developed for their cross-coupling to aryl and heteroaryl halides. The cross-coupled products were obtained in good to excellent yields. This method represents an efficient and facile installation of heterocyclic building blocks onto preexisting organic substructures.
Radical catalysis of kumada cross-coupling reactions using functionalized grignard reagents
Manolikakes, Georg,Knochel, Paul
supporting information; experimental part, p. 205 - 209 (2009/04/10)
(Chemical Equation Presented) Palladium, radically different: A wide range of polyfunctional aryl- and heteroarylmagnesium reagents undergo fast Kumada cross-couplings (see scheme) with functionalized aryl bromides in the presence of a palladium catalyst and an alkyl iodide as additive. These reactions proceed by a radical pathway.
