110216-65-4

Upstream product

• 122-39-4 diphenylamine 
• 18706-64-4 4-hydroxy-6-phenyl-2H-pyrano<3,2-c>quinoline-2,5(6H)-dione 
• 54289-77-9 3-acetyl-4-hydroxy-1-phenylquinolin-2(1H)-one 
• 14994-75-3 4-hydroxy-1-phenylquinolin-2(1H)-one 
• 54675-12-6 4-hydroxy-3-nitro-1-phenyl-2(1H)-quinolone 
• 110254-64-3 4-chloro-3-nitro-1-phenyl-2(1H)-quinolone 

Downstream Products

• 141945-49-5 4-amino-3-nitro-1-phenylquinolin-2(1H)-one 
• 141945-46-2 3-nitro-1-phenyl-4-triphenylphosphoranylidene-2(1H)-quinolone 
• 141945-43-9 4-oxo-5-phenyl-4,5-dihydro-1,2,5-oxadiazolo<3,4-c>quinolin 3-oxide 

Relevant academic research and scientific papers

Nucleophilic Substitution and Ring Closure Reactions of 4-Chloro-3-nitro-2-quinolones

4-Chloro-3-nitro-2-quinolones 3 obtained from the 4-hydroxy quinolones 1 by nitration and chlorination, reacted with sodium azide to the 4-azido derivatives 4 which cyclized on thermolysis to yield the furoxanes 5.Nucleophilic substitution reactions of 3

Methods for the Synthesis of 4-Azido-2(1H)-quinolones

4-Hydroxy-2-quinolones 1 are generally found to be converted to the 4-azidocompounds 3 via the 4-chloroquinolones 2, the 4-tosyloxyquinolones 6, or the 4-aminoquinolones 4, respectively.Choice of the reaction conditions and yields depend on the substituen