110254-64-3

Usage

InChI:InChI=1/C15H9ClN2O3/c16-13-11-8-4-5-9-12(11)17(10-6-2-1-3-7-10)15(19)14(13)18(20)21/h1-9H

Upstream product

• 14994-75-3 4-hydroxy-1-phenylquinolin-2(1H)-one 
• 54289-77-9 3-acetyl-4-hydroxy-1-phenylquinolin-2(1H)-one 
• 122-39-4 diphenylamine 
• 18706-64-4 4-hydroxy-6-phenyl-2H-pyrano<3,2-c>quinoline-2,5(6H)-dione 
• 20877-86-5 N-phenyl isatoic anhydride 
• 54675-12-6 4-hydroxy-3-nitro-1-phenyl-2(1H)-quinolone 

Downstream Products

• 141945-53-1 4-benzylamino-1-phenyl-3-nitro-2(1H)-quinolone 
• 141945-63-3 3-nitro-4-phenoxy-1-phenyl-2(1H)-quinolone 
• 193673-44-8 dimethyl (3-nitro-2-oxo-1-phenyl-1,2-dihydroquinolin-4-yl)malonate 
• 141945-46-2 3-nitro-1-phenyl-4-triphenylphosphoranylidene-2(1H)-quinolone 
• 141945-43-9 4-oxo-5-phenyl-4,5-dihydro-1,2,5-oxadiazolo<3,4-c>quinolin 3-oxide 
• 1027276-46-5 3,4-Diamino-1-phenyl-1H-quinolin-2-one 
• 141945-57-5 1-phenyl-4-phenylamino-3-nitro-2(1H)-quinolone 
• 141945-69-9 1-phenyl-3,4-diphenylthio-2(1H)-quinolone 
• 141945-66-6 3-nitro-1-phenyl-4-phenylthio-2(1H)-quinolone 
• 141945-49-5 4-amino-3-nitro-1-phenylquinolin-2(1H)-one 
• 141945-59-7 4-fluoro-3-nitro-1-phenyl-2(1H)-quinolone 
• 110216-65-4 4-azido-3-nitro-1-phenyl-2(1H)quinolone 
• 141945-60-0 4-methoxy-3-nitro-1-phenyl-2(1H)-quinolone 

Relevant academic research and scientific papers

Nucleophilic Substitution and Ring Closure Reactions of 4-Chloro-3-nitro-2-quinolones

4-Chloro-3-nitro-2-quinolones 3 obtained from the 4-hydroxy quinolones 1 by nitration and chlorination, reacted with sodium azide to the 4-azido derivatives 4 which cyclized on thermolysis to yield the furoxanes 5.Nucleophilic substitution reactions of 3

New Bronchodilators. 3. Imidazonaphthyridin-4(5H)-ones

In order to develop new oral bronchodilators, a series of novel imidazonaphthyridin-4(5H)-ones 5 were designed and synthesized.Some of these new heterocycles exhibited more potent bronchodilator activity in vitro and in vivo than theophylline.

Methods for the Synthesis of 4-Azido-2(1H)-quinolones

4-Hydroxy-2-quinolones 1 are generally found to be converted to the 4-azidocompounds 3 via the 4-chloroquinolones 2, the 4-tosyloxyquinolones 6, or the 4-aminoquinolones 4, respectively.Choice of the reaction conditions and yields depend on the substituen