110270-19-4

Usage

Uses

Used in Pharmaceutical Industry:
2-(D-XYLO-TETRAHYDROXYBUTYL)-4(R)-1,3-THIAZOLIDINE-4-CARBOXYLIC ACID is used as a potential pharmaceutical agent for its potential biological activities. 2-(D-XYLO-TETRAHYDROXYBUTYL)-4(R)-1,3-THIAZOLIDINE-4-CARBOXYLIC ACID's chiral nature and specific configuration may contribute to its therapeutic effects, although further research is needed to determine its exact applications and mechanisms of action.
Used in Research and Development:
2-(D-XYLO-TETRAHYDROXYBUTYL)-4(R)-1,3-THIAZOLIDINE-4-CARBOXYLIC ACID serves as a subject of study in research and development for its potential applications in various fields. Its unique structure and properties make it an interesting candidate for exploration, with the aim of discovering new uses and understanding its interactions with biological systems.

Upstream product

• 58-86-6 D-xylose 
• 52-89-1 l-cysteine hydrochloride 
• 52-90-4 L-Cysteine 
• 5328-37-0 L-arabinose 
• 10318-18-0 DL-cysteine hydrochloride 
• 1114-34-7 D-lyxose 

Downstream Products

• 921-01-7 D-cysteine 

Relevant academic research and scientific papers

Proton and Zinc(II) Complexes of 2-(Polyhydroxyalkyl)thiazolidine-4-carboxylic acid Derivatives

The protonation and zinc-ion co-ordination equilibria of 2-(polyhydroxyalkyl)thiazolidine-4-carboxylic acid derivatives have been studied by potentiometric titration in the range pH 1.5-8.In most cases the formation of complexes with a metal-to-ligand ratio of 1:2 was demonstrated, but at above pH 6 mixed-ligand complexes involving hydroxide-ion co-ordination were also observed.The protonation and complex-formation constants were shown to depend on the structure of the polyhydroxy chains.In the case of the protonation constants this is due to the rearrangement of the intramolecular hydrogen-bonding network, while the complex-formation constants depend on the conformation of the OH groups on the first carbon atoms of the polyol chains.

Thiazolidine-4(R)-carboxylic acids derived from sugars: Part I, C2-epimerisation in aqueous solutions.

Reactions of L-cysteine (1) with L-xylose, D-ribose, D-lyxose, D-arabnose, D-glucose, L-rhamnose, and-fucose in aqueoes ethanol yielded crystalline 2(S)-(polihydroxyalkyl)thiazolidine-4(R)-carboxylic acids.Likewise, glycolaldehyde and L-glyceraldehyde, D-xylose, L-arabinose, D-mannose, D-galactose, and D-fucose gave crystalline 2(R),4(R) epimers.The reaction of 1 and D-glycerinaldehyde gave a syrup mixture of 2(S),4(R) and 2(R),4(R) compounds.The same substrates, but with no ethanol present, gave the 2(S),4(R) epimers for glycolaldehyde, L-xylose, L-fucose, and L-arabinose, and the 2(R),4(R) epimers for D-lyxose, L-rhamnose, D-mannose, Dgalactose, and D-fucose.The reactions of D-ribose, D-arabinose, D-xylose, and D-glucose gave sirupy mixtures of epimers.The crystalline reaction products, when dissolved in water, undergo rapid epimerisation as reflected by mutarotation and changes in the 1H- and 13C-n.m.r. spectra.

Resolution of DL-Cysteine

The diastereomeric 4-thiazolidinecarboxylic acids 3 and 4, obtained by condensation of DL-cysteine (DL-1) with D-(+)-galactose (2), can be separated by crystallization.Ring cleavage of 3 or 4 gives L-cysteine (L-1) or D-cysteine (D-1), respectively.Instead of D-(+)-galactose other chiral aldoses can be employed as resolution agents.