110548-55-5

Basic information

• Product Name: (R)-α-cyclopropylbenzyl alcohol
• Synonyms: (R)-α-cyclopropylbenzyl alcohol
• CAS NO: 110548-55-5
• Molecular Weight: 148.205
• Mol File: 110548-55-5.mol
• Article Data: 19

Chemical Properties

• CAS DataBase Reference: (R)-α-cyclopropylbenzyl alcohol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-α-cyclopropylbenzyl alcohol(110548-55-5)
• EPA Substance Registry System: (R)-α-cyclopropylbenzyl alcohol(110548-55-5)

Safety Data

• Hazardous Substances Data: 110548-55-5(Hazardous Substances Data)

Upstream product

• 1667-00-1 benzylcyclopropane 
• 1007-03-0 1-phenyl-1-cyclopropylmethanol 
• 20525-76-2 dicyclopropylzinc 
• 100-52-7 benzaldehyde 
• 3481-02-5 cyclopropyl phenyl ketone 
• 108-05-4 vinyl acetate 
• 98-88-4 benzoyl chloride 

Relevant articles and documents

Visible-Light-Driven Catalytic Deracemization of Secondary Alcohols

Deracemization of racemic chiral compounds is an attractive approach in asymmetric synthesis, but its development has been hindered by energetic and kinetic challenges. Here we describe a catalytic deracemization method for secondary benzylic alcohols which are important synthetic intermediates and end products for many industries. Driven by visible light only, this method is based on sequential photochemical dehydrogenation followed by enantioselective thermal hydrogenation. The combination of a heterogeneous dehydrogenation photocatalyst and a chiral molecular hydrogenation catalyst is essential to ensure two distinct pathways for the forward and reverse reactions. These reactions convert a large number of racemic aryl alkyl alcohols into their enantiomerically enriched forms in good yields and enantioselectivities.

Amino Acid-Functionalized Metal-Organic Frameworks for Asymmetric Base–Metal Catalysis

We report a strategy to develop heterogeneous single-site enantioselective catalysts based on naturally occurring amino acids and earth-abundant metals for eco-friendly asymmetric catalysis. The grafting of amino acids within the pores of a metal-organic framework (MOF), followed by post-synthetic metalation with iron precursor, affords highly active and enantioselective (>99 % ee for 10 examples) catalysts for hydrosilylation and hydroboration of carbonyl compounds. Impressively, the MOF-Fe catalyst displayed high turnover numbers of up to 10 000 and was recycled and reused more than 15 times without diminishing the enantioselectivity. MOF-Fe displayed much higher activity and enantioselectivity than its homogeneous control catalyst, likely due to the formation of robust single-site catalyst in the MOF through site-isolation.

Chiral amino-pyridine-phosphine tridentate ligand, manganese complex, and preparation method and application thereof

The invention discloses a chiral amino-pyridine-phosphine tridentate ligand, a manganese complex, and a preparation method and application thereof. The chiral amino-pyridine-phosphine tridentate ligand is shown as a formula II, and the manganese complex of the chiral amino-pyridine-phosphine tridentate ligand can be used for efficiently catalyzing and hydrogenating ketone compounds to prepare chiral alcohol compounds in a high enantioselectivity mode. The chiral amino-pyridine-phosphine tridentate ligand and the manganese complex are simple in synthesis process, good in stability, high in catalytic activity and mild in reaction conditions.