110550-27-1Relevant articles and documents
The myo-1,2-diaminocyclitol scaffold defines potent glucocerebrosidase activators and promising pharmacological chaperones for gaucher disease
Trapero, Ana,Llebaria, Amadeu
supporting information; experimental part, p. 614 - 619 (2011/10/08)
A series of cyclitol derivatives with myo-configuration are β-glucocerebrosidase (GCase) inhibitors and show excellent characteristics for the development of pharmacological chaperones for enzyme deficiency in Gaucher disease (GD). The most potent inhibit
Synthesis of cyclitols via ring-closing metathesis
Kornienko, Alexander,D'Alarcao, Marc
, p. 827 - 829 (2007/10/03)
A convenient synthesis of enantiomerically pure and differentially protected L-chiro- and myo-inositols as well as conduritols B and F from 2,3,4-tri-O-benzyl-D-xylopyranose via ring-closing metathesis is reported. The facile synthesis of conduritol B con