110694-70-7Relevant academic research and scientific papers
Modulating β-arrestin 2 recruitment at the δ- And μ-opioid receptors using peptidomimetic ligands
Altman, Ryan A.,Blaine, Arryn T.,Cassell, Robert J.,Cummins, Benjamin R.,Johnson, David K.,Meqbil, Yazan J.,Mores, Kendall L.,Sharma, Krishna K.,Su, Hongyu,Van Rijn, Richard M.
, p. 1958 - 1967 (2021)
μ-Opioid receptor agonists provide potent and effective acute analgesia; however, their therapeutic window narrows considerably upon repeated administration, such as required for treating chronic pain. In contrast, bifunctional μ/δ opioid agonists, such a
