110716-75-1

Upstream product

• 4504-43-2 2-(phenylamino)cyclohexa-1-one 
• 38253-21-3 2-(N-ethyl-anilino)-cyclohexanone 
• 86099-82-3 2-(N-isopropylanilino)cyclohexanone 
• 38253-22-4 2-(N-phenylethylanilino)cyclohexanone 
• 591-50-4 iodobenzene 
• 286-20-4 cyclohexene oxide 
• 62-53-3 aniline 
• 286-20-4 cyclohexane-1,2-epoxide 
• 98-95-3 nitrobenzene 
• 18713-90-1 7-phenyl-7-aza-bicyclo[4.1.0]heptane 
• 5456-63-3 trans-2-aminocyclohexanol hydrochloride 
• 1056477-06-5 2-bromocyclohexanone 
• 108-94-1 cyclohexanone 
• 62509-73-3 cyclohex-2-en-1-yl phenylcarbamate 

Downstream Products

• 109128-84-9 (+/-)-trans-2-(N-Methyl-N-phenylamino)cyclohexanol 
• 101043-30-5 trans-1-Chloro-2-(phenylamino)-cyclohexane 
• 110674-21-0 C₁₃H₁₉NO₂ 
• 822-67-3 Cyclohex-2-enol 
• 1220636-79-2 C₁₄H₁₉NO₂ 
• 30303-39-0 trans-N,N'-diphenyl-1,2-cyclohexanediamine 
• 18713-90-1 7-phenyl-7-aza-bicyclo[4.1.0]heptane 

Relevant academic research and scientific papers

Differentiation of Epoxide Enantiomers in the Confined Spaces of an Homochiral Cu(II) Metal-Organic Framework by Kinetic Resolution

TAMOF-1, a homochiral metal-organic framework (MOF) constructed from an amino acid derivative and Cu(II), was investigated as a heterogeneous catalyst in kinetic resolutions involving the ring opening of styrene oxide with a set of anilines. The branched

Unravelling a new class of chiral organocatalyst for asymmetric ring-opening reaction of meso epoxides with anilines

Chiral sulfinamide based organocatalyst 11 was synthesized from readily available starting materials and used for the asymmetric ring-opening (ARO) reaction of meso epoxides with anilines. A high yield (up to 95%) of chiral β-amino alcohols with excellent

Synthesis and structure of an air-stable bis(pentamethylcyclopentadienyl) zirconium pentafluorbezenesulfonate and its application in catalytic epoxide ring-opening reactions

An air-stable mononuclear complex of bis(pentamethylcyclopentadienyl) zirconium pentafluorbezenesulfonate was successfully synthesized by treating C6F5SO3Ag with [(CH3)5Cp]2ZrCl2, which showed the cationic uninuclear structure of [{(CH3)5Cp}2Zr(CH3CN)2(H2O)][OSO2C6F5]2·CH3CN (1) confirmed by the X-ray analysis. Complex 1 was also characterized by other techniques and found to have the good nature of air-stability, water tolerance, thermally-stability and strong Lewis-acidity. Moreover, the complex showed high catalytic activity and recyclability in catalytic epoxide ring-opening reactions by amines or alcohols. This catalytic system affords a simple and efficient approach for synthesis of β-amino alcohols or β-alkoxy alcohols.

Copper-catalyzed arylation of beta-amino alcohols.

[reaction: see text] Methods for synthesizing N-aryl beta-amino alcohols and O-aryl beta-amino alcohols are described. The presence of a neighboring hydroxyl or amino group, respectively, is thought to activate beta-amino alcohols toward these transformations. These protocols significantly increase access to a variety of arylated beta-amino alcohols.

Desymmetric ring-opening of meso-epoxides with anilines: A simple way to chiral β-amino alcohols

Chiral β-amino alcohols were afforded by desymmetric ring-opening of meso-epoxides with anilines catalyzed by chiral Yb triflate complex in up to 80.1% ee.

An efficient method for the cleavage of aziridines using hydroxyl compounds

A variety of N-activated aziridines were opened with water, primary, allylic, and propargyl alcohols at rt in high yield using a catalytic amount of Sn(OTf)2 or BF3·OEt2. (C) 2000 Elsevier Science Ltd.

Development of Solvent-Dispersible Coordination Polymer Nanocrystals and Application as Efficient Heterogeneous Catalysts

Nonporous coordination polymers (CPs) constructed from flexible bridging ligands have seldom been utilized in practical applications, owing to limited solubility and/or stability in most solvents. Here we have produced nanocrystal coordination polymers (N

Studies on ring cleavage of aziridines with hydroxyl compounds

Ring cleavage of a variety of N-substituted aziridines has been studied with hydroxyl compounds (primary, secondary, allylic and tertiary). It was observed that the cleavage reaction was very facile in the presence of BF3·OEt2 and Sn(OTf)2. Whereas the aziridine opening reaction was facile with primary and secondary alcohols, hindered alcohols took longer (2 days). However, with the help of microwave radiation, the cleavage reaction with hindered alcohols could be achieved in a very short period (15min). Phenols could only cleave aziridines under microwave irradiation.

Efficient synthesis of β-amino alcohols catalyzed by niobium pentachloride: Regioselective ring opening of epoxides with aromatic amines

Epoxides undergo a rapid ring-opening reaction with aromatic amines catalyzed by niobium pentachloride under mild reaction conditions. All the reactions were carried out at room temperature to afford the corresponding β-amino alcohols in excellent yields

Cu2+, Zn2+, and Ni2+ Complexes of C2-Symmetric Pseudopeptides with an Aromatic Central Spacer

Two new tetradentate C2-symmetric pseudopeptidic ligands derived from Val and Phe containing two amino and two amido groups and a central o-substituted aromatic spacer have been prepared. Their complexes with Cu2+, Zn2+, a