110822-84-9

Upstream product

• 77287-34-4 formamide 
• 67-56-1 methanol 
• 141-46-8 Glycolaldehyde 
• 76-05-1 trifluoroacetic acid 

Downstream Products

• 2488-95-1 1,2-bis(2'-hydroxyethyl)-hydrazine 
• 30934-97-5 2,2-dimethoxyethanol 
• 123172-65-6 4-Hydroxy-3,3-diphenyl-dihydro-furan-2-one 
• 141-46-8 Glycolaldehyde 
• 57200-23-4 3-phenyl-2(5H)-furanone 
• 123172-69-0 (E)-4-Hydroxy-2-phenyl-but-2-enoic acid methyl ester 
• 115869-43-7 (tert-butyldiphenylsilanyloxy)acetaldehyde 
• 312583-37-2 4⁽⁵⁾-(3,5-dimethoxyphenyl)-1H-imidazole 
• 944541-40-6 C₂₂H₂₆FN₃O₃ 
• 156386-82-2 trans-γ-3-benzoylprop-2-en-1-ol 

Relevant academic research and scientific papers

Direct photophysical evidence for quenching of the triplet excited state of 2,4,6-triphenyl(thia)pyrylium salts by 2,3-diaryloxetanes

The thiapyrylium salt 1b is an efficient electron-transfer photosensitizer in the preparative irradiation of trans,-trans-2,3-diphenyl-4-methyloxetane (2a). Previously, the reaction has been assumed to occur through the triplet excited state of 1b, which has a very high intersystem crossing yield (φISC = 0.97). In the present report, direct evidence for triplet quenching in the oxidative cycloreversion of the 2,3-diaryloxetanes is provided. The rate constants kq(T1) and the free energy changes of the electron transfer ΔGET(T1) have been determined for the reaction between 1b and oxetanes 2a-d and 2a′. The process has been found to be exergonic in all cases except for 2d; this agrees with the fact that no photoproduct was obtained in the preparative irradiation of 1b in the presence of 2d. Good correlation between kq(T1) and ΔGET(T1) was observed, confirming the involvement of the excited triplet state in the reaction mechanism.

Insights into the existing form of glycolaldehyde in methanol solution: An experimental and theoretical investigation

Glycolaldehyde (HOCH2CHO, GA), the simplest molecule containing both hydroxyl and aldehyde groups, is structurally the most elementary member of monosaccharide sugars, which may provide new clues for probing the origin of life on planets like the Earth. Uncovering the existing state of GA in solution systems is an important scientific issue. Generally, methanol is used as the main mobile phase in the liquid chromatography analysis of GA, but the state of GA existing in methanol solution remains unknown, thus making it difficult to analyse GA accurately. Herein, the state and dynamic equilibrium of GA in methanol solution were systematically studied by UV-visible spectroscopy, nuclear magnetic resonance (1H-NMR) spectroscopy, liquid chromatography mass spectrometry (LC-MS) and density functional theory (DFT) calculations. The results demonstrated that the equilibrium component of GA in methanol solution is different from that in aqueous solution and that glycolaldehyde hemiacetal (GAHA) is a dominant component (>90%). Laying the foundation for experimental analysis, the transformation of different components at equilibrium was studied using DFT. The results confirm that hydrogen bonding-induced proton transfer occurs between the components at equilibrium. This work provides an important reference for the analysis of sugars and related compounds in various biochemical reactions.

Synthesis method of 1, 4-dioxane-2, 5-diol

The invention discloses a synthesis method of 1, 4-dioxane-2, 5-diol. The synthesis method includes: taking chloroacetaldehyde as the raw material, firstly carrying out reaction with sodium bisulfiteor sodium metabisulfite to generate chloroacetaldehyde omega-sulfonic acid, carrying out aldehyde group protection, then adding acid for precipitation, and then decomposing the chloroacetaldehyde omega-sulfonic acid into 1, 4-dioxane-2, 5-diol under a strong alkaline condition of sodium hydroxide. Compared with other process routes, the raw materials adopted by the invention are easily availableand low in price, and the production cost is greatly reduced; moreover, the adopted chemical reaction is mild in conditions and easy to operate, therefore the method is more suitable for large-scale industrial production.

Silica Metal Oxide Vesicles Catalyze Comprehensive Prebiotic Chemistry

It has recently been demonstrated that mineral self-assembled structures catalyzing prebiotic chemical reactions may form in natural waters derived from serpentinization, a geological process widespread in the early stages of Earth-like planets. We have s

Stoichiometric hydroformylation of coordinated acetone

The bridging acetone in Cp2Zr [(μ-OC)Mo-(CO)2Cp] [μ-η2,η1-CMe2O)Zr(Me)Cp2] (1) undergoes CO insertion into its Zr-C bond, with the oxygen of the new η2-acyl ligand displacing the