30934-97-5Relevant articles and documents
Preparation method of 2, 2-dimethoxyacetaldehyde
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Paragraph 0026; 0027; 0029; 0030; 0032; 0033; 0035; 0036, (2020/07/21)
The invention discloses a preparation method of 1, 2-dimethoxyacetaldehyde. Hydroxyacetaldehyde is adopted as a raw material and a methanol raw material, S2O8 /Zn-MCM-41 solid superacid is adopted as a catalyst, the acidity is high and 2, 2-methoxyethanol can be obtained with high selectivity, then 2, 2-methoxyacetaldehyde is obtained under the action of an oxidizing agent, the product is easy to separate, and the purity of dimethoxyacetaldehyde reaches up to 95% or above.
Heterocyclic Compound
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Paragraph 2270; 2271, (2018/06/15)
The present invention provide a compound having an orexin receptor antagonistic activity, which is expected to be useful as medicaments such as agents for the prophylaxis or treatment of sleep disorder, depression, anxiety disorder, panic disorder, schizophrenia, drug dependence, Alzheimer's disease and the like. The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof.
Mechanistic insights into the production of methyl lactate by catalytic conversion of carbohydrates on mesoporous Zr-SBA-15
Yang, Lisha,Yang, Xiaokun,Tian, Elli,Vattipalli, Vivek,Fan, Wei,Lin, Hongfei
, p. 207 - 216 (2015/12/04)
The as-synthesized Zr-SBA-15 catalysts with tunable mesoporous structures showed excellent catalytic performance for the conversion of carbohydrates to methyl lactate in a "one-pot" process using near-critical methanol or methanol-water mixture as the solvents. The effects of reaction conditions, including temperature, reaction time, and catalyst loading amount, on the conversions of carbohydrates and the yields of methyl lactate were investigated. The high yields of methyl lactate, up to 41% and 44%, were produced from pentose and hexose, respectively, in the near-critical methanol at 240 °C. Moreover, the Si/Zr ratio of the Zr-SBA-15 catalysts profoundly affected the Lewis acidity and therefore the catalytic activity and selectivity to methyl lactate in the conversion of carbohydrates. The pore size of the Zr-SBA-15 catalysts, tuned by the synthesis temperature, strongly affected the formation of solid residues. The key intermediates such as glyceraldehyde, glycolaldehyde, and pyruvaldehyde were used as probe reactants to understand the mechanism. The role of the Zr-SBA-15 catalyst in the aldol- and retro-aldol condensation, isomerization, and Cannizzaro reactions of carbohydrates and their derivatives was discussed. Furthermore, 28% and 27% yields of methyl lactate were obtained from cellulose and starch, respectively, in methanol-water mixture (5 wt% water and 95 wt% methanol) at 240 °C. The Zr-SBA-15 catalyst was relatively stable in short term without regeneration.
