110841-22-0

Upstream product

• 130831-47-9 3-chloro-2-methyl-4-phenyl-3,4-dihydro-2H-isoquinolin-1-one 
• 108960-88-9 2-methyl-4-phenylisoquinolin-1(2H)-one 
• 101118-74-5 2-(2-chloro-1-phenyl-vinyl)-benzoic acid methylamide 
• 88070-48-8 N-methylbenzamide 
• 175857-53-1 N-diphenylphosphinoylmethyl-N-methyl-2-benzoylbenzamide 
• 865163-32-2 2-[2-(benzyl-methyl-amino)-1-phenyl-ethyl]-benzoic acid ethyl ester 
• 21921-91-5 2-Benzyl-N-methyl-benzamid 
• 5398-11-8 3-phenylphthalide 

Downstream Products

• 28102-51-4 1,2,3,4-tetrahydro-2-methyl-4-phenylisoquinoline 

Relevant academic research and scientific papers

Oxazoline as a useful tool in organic synthesis: Preparation of 4-aryl-1,2,3,4-tetrahydroisoquinoline alkaloid skeleton

New direct strategy for the synthesis of 4-aryl-1,2,3,4- tetrahydroisoquinolines. The key steps are based on oxazoline chemistry: nucleophilic substitution in an ortho-methoxyphenyloxazoline with a Grignard reagent and a 1,6-conjugate addition of a lithiu

A new synthetic route to 2-alkyl-4-aryl-1(2H)-isoquinolones and 2-alkyl-4-aryl-1,2,3,4-tetrahydroisoquinolines

4-Aryl and heteroaryl-1(2H)-isoquinolones have been prepared by base promoted cyclization of phosphorylated o-aroyl and heteroaroyl benzamides. Subsequent reduction of the carbonyl and styryl functions of the annulated products has given rise to 4-aryl-1,2,3,4-tetrahydroisoquinolines.

An Efficint Synthesis of 4-Aryl-1,2,3,4-terahydroisoquinolines

A general synthesis of N-methyl-1,2,3,4-tetrahydroisoquinolines from 3-aryl phthalides is described.