1109284-38-9 Usage
Bicyclic structure
A molecule with two interconnected rings, specifically a bicyclo[4.1.0]heptane framework.
Fluorine atom positions
2 and 2'
Two fluorine atoms are attached to the carbon atoms at the 2 and 2' positions, which are opposite each other in the bicyclic structure.
Oxygen atom position
7
An oxygen atom is located at the 7 position, which is adjacent to one of the carbon atoms in the bicyclic structure.
Synthetic intermediate
2,2-Difluoro-7-oxa-bicyclo[4.1.0]heptane is used as a precursor in organic synthesis, allowing for the creation of more complex molecules.
Applications in pharmaceuticals and agrochemicals
The compound has potential uses in the development of medications and chemicals for agricultural purposes.
Relevance to materials science
2,2-Difluoro-7-oxa-bicyclo[4.1.0]heptane may be used in the development of novel polymers or as a building block for more complex molecules in materials science.
Unique structure and functional groups
The combination of its bicyclic structure, fluorine and oxygen atoms make it a valuable tool for research and development in various fields of chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 1109284-38-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,0,9,2,8 and 4 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1109284-38:
(9*1)+(8*1)+(7*0)+(6*9)+(5*2)+(4*8)+(3*4)+(2*3)+(1*8)=139
139 % 10 = 9
So 1109284-38-9 is a valid CAS Registry Number.
1109284-38-9Relevant articles and documents
Optimization of microtubule affinity regulating kinase (MARK) inhibitors with improved physical properties
Sloman, David L.,Noucti, Njamkou,Altman, Michael D.,Chen, Dapeng,Mislak, Andrea C.,Szewczak, Alexander,Hayashi, Mansuo,Warren, Lee,Dellovade, Tammy,Wu, Zhenhua,Marcus, Jacob,Walker, Deborah,Su, Hua-Poo,Edavettal, Suzanne C.,Munshi, Sanjeev,Hutton, Michael,Nuthall, Hugh,Stanton, Matthew G.
supporting information, p. 4362 - 4366 (2016/08/18)
Inhibition of microtubule affinity regulating kinase (MARK) represents a potentially attractive means of arresting neurofibrillary tangle pathology in Alzheimer's disease. This manuscript outlines efforts to optimize a pyrazolopyrimidine series of MARK in
PYRAZOLO[1,5-A]PYRIDINES AS MARK INHIBITORS
-
Page/Page column 44; 51, (2010/04/03)
The invention encompasses pyrazolo[1,5-a]pyridine derivatives which selectively inhibit microtubule affinity regulating kinase (MARK) and are therefore useful for the treatment or prevention of Alzheimer's disease. Pharmaceutical compositions and methods of use are also included.
