111057-34-2

Basic information

• Product Name: 1-Thio-α-D-mannose Natriumsalz
• Synonyms: 1-Thio-α-D-mannose Natriumsalz;1-Thio-alpha-D-mannopyranose monosodium salt
• CAS NO: 111057-34-2
• Molecular Formula: C₆H₁₁O₅S*Na
• Molecular Weight: 218.204
• Product Categories: Carbohydrates
• Mol File: 111057-34-2.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Thio-α-D-mannose Natriumsalz(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Thio-α-D-mannose Natriumsalz(111057-34-2)
• EPA Substance Registry System: 1-Thio-α-D-mannose Natriumsalz(111057-34-2)

Safety Data

• Hazardous Substances Data: 111057-34-2(Hazardous Substances Data)

Usage

Chemical composition

A thio-substituted alpha-D-mannose molecule combined with a sodium salt.

Derived from

A derivative of mannose, a type of sugar.

Unique feature

A sulfur atom replaces one of the oxygen atoms within the molecule.

Common uses

Chemical and biological research, pharmaceutical applications.

Interactions

Ability to interact with proteins and enzymes.

Utility

Useful for studying and modifying biological processes.

Therapeutic potential

Ability to modulate certain cellular functions.

Fields of application

Medicine, biochemistry, and biotechnology.

Upstream product

• 19879-84-6 2,3,4,6-tetra-O-acetyl-1-thio-α-D-mannopyranoside 

Downstream Products

• 1189747-25-8 1,3-bis(α-D-mannopyranosyldithiomethylene)benzene 
• 1189747-27-0 1,2-bis(α-D-mannopyranosyldithiomethylene)benzene 
• 1189747-29-2 1,3,5-tris(α-D-mannopyranosyldithiomethylene)benzene 
• 1189747-33-8 (α-D-mannopyranosyldithiomethylene)benzene 
• 1309456-99-2 C₂₅H₃₆F₄N₄O₁₁S 

Relevant articles and documents

Interactions of aromatic mannosyl disulfide derivatives with Concanavalin A: synthesis, thermodynamic and NMR spectroscopy studies

α-d-Mannopyranosyl units were attached to an aromatic scaffold through disulfide linkages to obtain mono- to trivalent glycosylated ligands for lectin binding studies. Isothermal titration calorimetric (ITC) measurements indicated that binding affinities of these derivatives to Concanavalin A (Con A) were comparable to or slightly higher than that of methyl α-d-mannopyranoside (Ka values in the range of 104 M-1). The stoichiometries of the lectin-ligand complexes were in agreement with the formal valencies (1-3) of the respective ligands indicating cross-linking in interactions with the di- and trivalent derivatives. Multivalency effects could not, however, be observed with the latter. These ligands were shown to bind to the carbohydrate binding site of Con A using saturation transfer difference (STD) NMR competition experiments.