1111096-29-7

Basic information

• Product Name: Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)furan-3-carboxylate
• Synonyms: 4-(Methoxycarbonyl)furan-2-boronic acid, pinacol ester;Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)furan-3-carboxylate
• CAS NO: 1111096-29-7
• Molecular Formula: C12H17BO5
• Molecular Weight: 252.07138
• Mol File: 1111096-29-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)furan-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)furan-3-carboxylate(1111096-29-7)
• EPA Substance Registry System: Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)furan-3-carboxylate(1111096-29-7)

Safety Data

• Hazardous Substances Data: 1111096-29-7(Hazardous Substances Data)

Usage

General Description

Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)furan-3-carboxylate is a chemical compound with the molecular formula C13H18B O5. It is a furan derivative that contains a boron atom and is commonly used as a building block in organic synthesis. Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)furan-3-carboxylate is often utilized as a reagent in the preparation of various pharmaceuticals and agrochemicals. It is known for its versatile reactivity and is a valuable intermediate in the production of biologically active compounds. Additionally, it is important to handle this compound with care due to its potential health hazards, including skin and eye irritation, and it should only be used by individuals with proper training and protective equipment.

Upstream product

• 13129-23-2 methyl furan-3-carboxylate 
• 73183-34-3 bis(pinacol)diborane 
• 488-93-7 3-Furoic acid 
• 25015-63-8 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane 
• 1073354-94-5 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)furan-3-carboxylic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 

Relevant articles and documents

Synthesis of Raputimonoindoles A–C and Congeners

The first synthesis of raputimonoindole A from the tree Raputia praetermissa (Rutaceae) is reported, starting from indole-5-carbaldehyde. The key step is Braun′s diastereoselective Heck–Suzuki cascade that assembled the prenylated methylenetetrahydrofuran moiety. The unsubstituted indole enamine functionality was tolerated, and the absolute configuration of naturally occurring raputimonoindole A is assigned as (R,R). Raputimonoindole B was accessed by Ir-catalyzed C–H activation/borylation followed by Suzuki–Miyaura cross-coupling. Two biosynthetically related 5-(dihydrofuran-2-yl)indole derivatives from R. simulans were synthesized by ring-closing metathesis, and their absolute configurations were determined.

CYCLIC AMINE SUBSTITUTED OXAZOLIDINONE CETP INHIBITOR

CCompounds having the structure of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compound of Formula I, A3 is a substitiuted phenyl group or indanyl group.Formula (I)