18068-06-9

Basic information

• Product Name: 4-Methoxycyclohexanol
• Synonyms: 4-Metho×ycyclohe×anol;4-methoxycyclohexan-1-ol
• CAS NO: 18068-06-9
• Molecular Formula: C₇H₁₄O₂
• Molecular Weight: 130.19
• Mol File: 18068-06-9.mol
• Article Data: 29

Chemical Properties

• Boiling Point: 217 °C at 760 mmHg
• Flash Point: 89.1 °C
• Appearance: /
• Density: 0.99g/cm³
• Vapor Pressure: 0.0292mmHg at 25°C
• Refractive Index: 1.457
• Storage Temp.: 2-8°C
• PKA: 14.98±0.40(Predicted)
• CAS DataBase Reference: 4-Methoxycyclohexanol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Methoxycyclohexanol(18068-06-9)
• EPA Substance Registry System: 4-Methoxycyclohexanol(18068-06-9)

Safety Data

• Hazardous Substances Data: 18068-06-9(Hazardous Substances Data)

Usage

General Description

4-Methoxycyclohexanol is a chemical compound that belongs to the family of cyclohexanols. It's a secondary alcohol, represented by the formula C7H14O2. This organic compound is liquid in state, and frequently serves in industrial applications due to its chemical properties. As a moderately polar compound, 4-Methoxycyclohexanol exhibits solvent properties, enabling it to dissolve a range of organic materials. It's primarily used in the manufacturing of flavors, perfumes, essential oils, and pharmaceutical industries. It's recommended to handle it with care, given its classification as an irritant to eyes, skin, and the respiratory system.

InChI:InChI=1/C7H14O2/c1-9-7-4-2-6(8)3-5-7/h6-8H,2-5H2,1H3

Upstream product

• 150-76-5 4-methoxy-phenol 
• 13482-23-0 4-methoxycyclohexanone 
• 126931-29-1 4-((tert-butyldimethylsilyl)oxy)cyclohexan-1-ol 
• 55145-45-4 4-(tert-butyldimethylsilyloxy)cyclohexanone 
• 123-31-9 hydroquinone 
• 637-88-7 1,4-Cyclohexanedione 
• 56292-99-0 4-methoxycyclohexanone ethylene ketal 
• 4746-97-8 cyclohexanedione monoethylene ketal 
• 22428-87-1 4,4-ethylenedioxycyclohexan-1-ol 
• 556-48-9 1,4-Cyclohexanediol 
• 74-88-4 methyl iodide 
• 931-71-5 cis-1,4-cyclohexanediol 
• 6995-79-5 cyclohexane-1,4-diol 

Downstream Products

• 100249-54-5 1,4-dimethoxycyclohexane 
• 103319-11-5 2-acetyl-4-methoxycyclohexanone 
• 19305-94-3 4-Bromadamantandion-(2,6) 
• 39751-07-0 adamantane-2,6-dione 
• 1026848-11-2 4-methyl-3-oxo-pentanoic acid 4-methoxy-cyclohexyl ester 
• 92301-93-4 Toluene-4-sulfonic acid 4-methoxy-cyclohexyl ester 
• 13482-23-0 4-methoxycyclohexanone 
• 99183-17-2 4-methoxycyclohexyl acetate 
• 96274-52-1 1-[2-(4-chloro-benzhydryloxy)-ethyl]-4-[2-(4-methoxy-cyclohexyloxy)-ethyl]-piperazine 
• 15766-93-5 cyclohex-3-enyl-methyl ether 
• 387825-48-1 cis-8-methoxy-1,3-diazaspiro[4.5]decane-2,4-dione 
• 637-88-7 1,4-Cyclohexanedione 
• 4746-97-8 cyclohexanedione monoethylene ketal 
• 41043-88-3 4-acetoxycyclohexanone 

Relevant articles and documents

Chemoselective and Tandem Reduction of Arenes Using a Metal–Organic Framework-Supported Single-Site Cobalt Catalyst

The development of heterogeneous, chemoselective, and tandem catalytic systems using abundant metals is vital for the sustainable synthesis of fine and commodity chemicals. We report a robust and recyclable single-site cobalt-hydride catalyst based on a porous aluminum metal–organic framework (DUT-5 MOF) for chemoselective hydrogenation of arenes. The DUT-5 node-supported cobalt(II) hydride (DUT-5-CoH) is a versatile solid catalyst for chemoselective hydrogenation of a range of nonpolar and polar arenes, including heteroarenes such as pyridines, quinolines, isoquinolines, indoles, and furans to afford cycloalkanes and saturated heterocycles in excellent yields. DUT-5-CoH exhibited excellent functional group tolerance and could be reusable at least five times without decreased activity. The same MOF-Co catalyst was also efficient for tandem hydrogenation–hydrodeoxygenation of aryl carbonyl compounds, including biomass-derived platform molecules such as furfural and hydroxymethylfurfural to cycloalkanes. In the case of hydrogenation of cumene, our spectroscopic, kinetic, and density functional theory (DFT) studies suggest the insertion of a trisubstituted alkene intermediate into the Co–H bond occurring in the turnover limiting step. Our work highlights the potential of MOF-supported single-site base–metal catalysts for sustainable and environment-friendly industrial production of chemicals and biofuels.

Synthesis method of 4-substituent cyclohexanone liquid crystal intermediate

The invention discloses a synthesis method of a 4-substituent cyclohexanone liquid crystal intermediate, which comprises the following step: carrying out oxidation catalytic reaction on 4-substituent cyclohexanol under the action of trichloroisocyanide urea to obtain the 4-substituent cyclohexanone liquid crystal intermediate. The method is high in reaction selectivity, high in yield, environment-friendly, simple in post-treatment and suitable for industrial production.

Synthetic method of cis-4-methoxycyclohexyl-1-carbamic acid

The invention provides a synthetic method of cis-4-methoxycyclohexyl-1-carbamic acid. The synthetic method includes the steps of catalytic hydrogenation, oxidative reaction, replacement reaction and hydrolytic reaction; the hydrolytic reaction is carried out in a microreactor, with a Jones reagent acting as an oxidant; barium hydroxide octahydrate is used as an alkaline material in the hydrolyticreaction. The synthetic method has few steps and shorter reaction time; the salt content in reaction wastewater is low, the content of heavy metals is low, and discharged waste is little; the finishedproduct has the content of 98% and above; the total reaction yield is 45% and above.