1114506-93-2Relevant academic research and scientific papers
Direct Oxygenation of C-H Bonds through Photoredox and Palladium Catalysis
Paul, Amrita,Shah, Sk. Sheriff,Shee, Maniklal,Singh, Amit Kumar,Singh, N. D. Pradeep
, p. 3426 - 3439 (2020/03/23)
This report presents the oxygenation of C-H bonds via the merger of photocatalysis and Pd catalysis. Herein, we describe the utilization of a photocatalyst to oxidize an organopalladium(II) intermediate to high-valent PdIII or PdIV intermediates, which promotes the formation of C-O bonds. The demonstrated method works efficiently with various directing groups, such as oxime ether and benzothiazole. The applicability of this direct C-O bond formation method is shown by synthesizing several metal complexes of 2-(benzo[d]thiazol-2-yl)phenol that can be used in organic light-emitting diodes and pharmaceuticals.
Rhodium(III)-Catalyzed ortho-Heteroarylation of Phenols through Internal Oxidative C-H Activation: Rapid Screening of Single-Molecular White-Light-Emitting Materials
Li, Bijin,Lan, Jingbo,Wu, Di,You, Jingsong
, p. 14008 - 14012 (2016/01/25)
Reported herein is the first example of a transition-metal-catalyzed internal oxidative C-H/C-H cross-coupling between two (hetero)arenes through a traceless oxidation directing strategy. Without the requirement of an external metal oxidant, a wide range of phenols, including phenol-containing natural products, can undergo the coupling with azoles to assemble a large library of highly functionalized 2-(2-hydroxyphenyl)azoles. The route provides an opportunity to rapidly screen white-light-emitting materials. As illustrative examples, two bis(triphenylamine)-bearing 2-(2-hydroxyphenyl)oxazoles, which are difficult to access otherwise, exhibit bright white-light emission, high quantum yield, and thermal stability. Also presented is the first example of the white-light emission, in a single excited-state intramolecular proton transfer system, of 2-(2-hydroxyphenyl)azoles, thus highlighting the charm of C-H activation in the discovery of new organic optoelectronic materials.
Synthesis of luminescent ethynyl-extended regioisomers of borate complexes based on 2-(2′-hydroxyphenyl)benzoxazole
Massue, Julien,Frath, Denis,Retailleau, Pascal,Ulrich, Gilles,Ziessel, Raymond
supporting information, p. 5375 - 5386 (2013/05/21)
A series of thirteen luminescent tetrahedral borate complexes based on the 2-(2′-hydroxyphenyl)benzoxazole (HBO) core is presented. Their synthesis includes the incorporation of an ethynyl fragment by Sonogashira cross-coupling reaction, with the goal of
Design, selection, and characterization of thioflavin-based intercalation compounds with metal chelating properties for application in alzheimer's disease
Rodriguez-Rodriguez, Cristina,Groot, Natalia Sanchez de,Rimola, Albert,Alvarez-Larena, Angel,Lloveras, Vega,et al.
experimental part, p. 1436 - 1451 (2009/07/30)
Metal chelation is considered a rational therapeutic approach for interdicting Alzheimer's amyloid pathogenesis. At present, enhancing the targeting and efficacy of metal-ion chelating agents through ligand design isa main strategy in the development of t
