111392-98-4Relevant academic research and scientific papers
Pigments of fungi. XLIV* synthesis of differentially protected chiral pentane-1,3,5-triol derivatives; confirmation of the absolute configuration of naturally occurring 3-acetoxy-2,3-dihydropiptoporic acid
Burns, Christopher J.,Gill, Melvyn,Saubern, Simon
, p. 1067 - 1079 (2007/10/03)
(R)-1-t-Butyldimethylsilyloxy-5-phenylmethoxypentan-3-ol (25), prepared in 68% yield and >99.9% enantiomeric excess over six steps from commercially available but-3-yn-1-ol by Katsuki-Sharpless epoxidation, was converted by way of its 3-methoxymethyl ethe
STUDIES ON ASYMMETRIC SYNTHESIS OF β-HYDROXY-δ-LACTONE INHIBITORS OF HMGCoA REDUCTASE 1. A NEW PREPARATION OF THE LACTONE MOIETY OF COMPACTIN
Bonadies, Francesco,Fabio, Romano Di,Gubbiotti, Andreina,Mecozzi, Sandro,Bonini, Carlo
, p. 703 - 706 (2007/10/02)
A new strategy for the preparation of chiral β-hydroxy-δ-lactone inhibitors of HMGCoA reductase is outlined: in particular the compactin lactone moiety has been elaborated by asymmetric epoxidation of the appropriate allylic alcohol and subsequent introdu
Synthesis of Saccharides and Related Polyhydroxylated Natural Products. 2. Simple Deoxyalditols
Ma, P.,Martin, V. S.,Masamune, S.,Sharpless, K. B.,Viti, S. M.
, p. 1378 - 1380 (2007/10/02)
Asymmetric epoxidation of allylic alcohols followed by selective hydride reduction provides a new route to chiral 1,3-diols and 1,3,5-triols; one of the 1,3,5-triols (21) is also synthesized from D-glucose.
