111466-34-3

Upstream product

• 111393-02-3 (R)-5-Acetoxy-3-methoxymethoxy-7-phenyl-heptanoic acid 
• 3277-89-2 phenethylmagnesium bromide 
• 3393-45-1 5,6-dihydro-pyran-2-one 
• 111466-32-1 (2S,3R)-4-t-butyldimethylsilyloxy-2,3-epoxy-pentan-1-ol 
• 111393-00-1 (S)-5-Benzyloxy-3-methoxymethoxy-pentanal 
• 111392-99-5 ((S)-5-Benzyloxy-3-methoxymethoxy-pentyloxy)-tert-butyl-dimethyl-silane 
• 111393-01-2 Acetic acid (S)-5-benzyloxy-3-methoxymethoxy-1-phenethyl-pentyl ester 
• 111392-98-4 (S)-1-Benzyloxy-5-(tert-butyl-dimethyl-silanyloxy)-pentan-3-ol 
• 111392-97-3 (S)-5-(tert-Butyl-dimethyl-silanyloxy)-pentane-1,3-diol 

Relevant academic research and scientific papers

A NEW STRATEGY FOR THE ENANTIOSELECTIVE SYNTHESIS OF THE δ-LACTONE MOIETY OF COMPACTIN AND MEVINOLIN

A new strategy for the preparation of optically active lactone analogues of the inhibitors of hydroxy-methylglutaryl-coenzyme A reductase is outlined.The lactone moiety has been elaborated by enzymatic resolution with porcine pancreas lipase of racemic 4-

STUDIES ON ASYMMETRIC SYNTHESIS OF β-HYDROXY-δ-LACTONE INHIBITORS OF HMGCoA REDUCTASE 1. A NEW PREPARATION OF THE LACTONE MOIETY OF COMPACTIN

A new strategy for the preparation of chiral β-hydroxy-δ-lactone inhibitors of HMGCoA reductase is outlined: in particular the compactin lactone moiety has been elaborated by asymmetric epoxidation of the appropriate allylic alcohol and subsequent introdu