111392-99-5

Upstream product

• 111392-98-4 (S)-1-Benzyloxy-5-(tert-butyl-dimethyl-silanyloxy)-pentan-3-ol 
• 111466-32-1 (2S,3R)-4-t-butyldimethylsilyloxy-2,3-epoxy-pentan-1-ol 
• 111392-97-3 (S)-5-(tert-Butyl-dimethyl-silanyloxy)-pentane-1,3-diol 
• 3393-45-1 5,6-dihydro-pyran-2-one 

Downstream Products

• 111393-00-1 (S)-5-Benzyloxy-3-methoxymethoxy-pentanal 
• 111466-34-3 3β-hydroxy-5β-<(2-phenyl)ethyl>-δ-lactone 
• 111393-01-2 Acetic acid (S)-5-benzyloxy-3-methoxymethoxy-1-phenethyl-pentyl ester 
• 111393-02-3 (R)-5-Acetoxy-3-methoxymethoxy-7-phenyl-heptanoic acid 
• 86117-01-3 (4R,6R)-(+)-4-hydroxy-6-(2-phenylethyl)-tetrahydro-2H-pyran-2-one 

Relevant academic research and scientific papers

STUDIES ON ASYMMETRIC SYNTHESIS OF β-HYDROXY-δ-LACTONE INHIBITORS OF HMGCoA REDUCTASE 1. A NEW PREPARATION OF THE LACTONE MOIETY OF COMPACTIN

A new strategy for the preparation of chiral β-hydroxy-δ-lactone inhibitors of HMGCoA reductase is outlined: in particular the compactin lactone moiety has been elaborated by asymmetric epoxidation of the appropriate allylic alcohol and subsequent introdu