111491-96-4Relevant articles and documents
CamTHP*OH: A camphor-derived δ-lactol auxiliary for the effective desymmetrization of attached glycinamide residues. Asymmetric synthesis of α-amino carbonyl compounds
Dixon, Darren J.,Horan, Richard A. J.,Monck, Nathaniel J. T.
, p. 4423 - 4426 (2007/10/03)
(Chemical equation presented) Stereoselective allylation of camphor and subsequent terminal hydroformylation affords a new δ-lactol auxiliary (camTHP*OH) on multigram scale. Stereoselective condensation with glycine dimethylamide and Cbz protection afford
N-PROTECTED α-AMINOMETHYLKETONE ANALOGUES OF C-TERMINAL p-NITROBENZYL-3-KETOESTERS OF N-PROTECTED AMINO ACIDS
Mansour, Tarek S.,Evans, Coleen A.
, p. 667 - 672 (2007/10/02)
Hydrogenolysis of N-protected amino acid p-nitrobenzyl-3-ketoesters over palladium on charcoal in THF gave N-protected α-amino methyl ketones in 45-83percent isolated yield.