111601-13-9Relevant academic research and scientific papers
Transition-Metal-Free Heterocyclization of 1,3-Diynes with Nitriles in the Presence of Aqueous Potassium Hydroxide: Synthesis of 2,4-Disubstituted 5-[(E)-2-Phenylethenyl]-1,3-oxazoles
Ming, Ling,Tang, Jialiang,Zhao, Xiaoming
, p. 2499 - 2505 (2014)
A transition-metal-free heterocyclization of 1,3-diynes and nitriles in the presence of either aqueous potassium hydroxide or cesium hydroxide in 1,4-dioxane at 100°C was realized. This method provided stereoselectively 2,4-disubstituted 5-[(E)-2-phenylethenyl]-1,3-oxazoles in moderate to good yields.
Regioselective formation of 2,4,5-trisubstituted oxazoles through transition-metal free heterocyclization of 1,3-diynes with N, O -bis(trimethylsiyl)acetamide
Zhang, Liang,Zhao, Xiaoming
, p. 184 - 186 (2015)
Transition-metal free heterocyclization reaction of 1,3-diynes with N,O-bis(trimethylsiyl)acetamide was accomplished in the presence of t-BuOK and acetonitrile at 120 °C. This method regioselectively gave 2,4,5-trisubstituted oxazoles in yields up to 97%.
A (E)- 2, 4, 5 - tri-substituted - (1 - propenyl) oxazole ring compound and its preparation method
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Paragraph 0035; 0039; 0047; 0048, (2017/04/21)
The present invention relates to an (E)-2,4,5-trisubstituted-(1-propenyl)oxazole ring compound, which has the following structural formula, wherein R1 and R2 are optionally selected from a benzene ring or a substituted group-containing aryl group, and are
Transition-metal-free heterocyclization of 1,3-diynes with nitriles in the presence of aqueous potassium hydroxide: Synthesis of 2,4-disubstituted 5-[(E)-2-Phenylethenyl]-1,3-oxazoles
Ming, Ling,Tang, Jialiang,Zhao, Xiaoming
, p. 2499 - 2505 (2014/11/08)
A transition-metal-free heterocyclization of 1,3-diynes and nitriles in the presence of either aqueous potassium hydroxide or cesium hydroxide in 1,4-dioxane at 100 °C was realized. This method provided stereoselectively 2,4-disubstituted 5-[(E)-2-phenylethenyl]-1,3-oxazoles in moderate to good yields. Georg Thieme Verlag Stuttgart New York.
Palladium-Catalyzed Reactions of Terminal Acetylenes and Olefins with Halo-1,3-azoles
Sakamoto, Takao,Nagata, Hideo,Kondo, Yoshinori,Shiraiwa, Masafumi,Yamanaka, Hiroshi
, p. 823 - 828 (2007/10/02)
The palladium-catalyzed reactions of 4-bromo- and 5-bromothiazoles, as well as 4-bromo and 5-bromooxazoles with terminal acetylenes gave ethynyl derivatives in 43-89percent yields, whereas the reactions of 2-bromothiazoles and iodo-N-methylimidazoles affo
