111945-91-6

Basic information

• Product Name: 4'-fluoro-5,6-dihydro-[1,1'-biphenyl]-3(4H)-one
• Synonyms: 4'-fluoro-5,6-dihydro-[1,1'-biphenyl]-3(4H)-one
• CAS NO: 111945-91-6
• Molecular Weight: 190.217
• Mol File: 111945-91-6.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: 4'-fluoro-5,6-dihydro-[1,1'-biphenyl]-3(4H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-fluoro-5,6-dihydro-[1,1'-biphenyl]-3(4H)-one(111945-91-6)
• EPA Substance Registry System: 4'-fluoro-5,6-dihydro-[1,1'-biphenyl]-3(4H)-one(111945-91-6)

Safety Data

• Hazardous Substances Data: 111945-91-6(Hazardous Substances Data)

Upstream product

• 5323-87-5 3-Ethoxycyclohex-2-en-1-one 
• 460-00-4 1-Bromo-4-fluorobenzene 
• 598-32-3 2-hydroxy-3-butene 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 15321-51-4 diiron nonacarbonyl 
• 827-87-2 1-(1-cyclopropylvinyl)-4-fluorobenzene 
• 504-02-9 1,3-cylohexanedione 
• 201230-82-2 carbon monoxide 
• 930-68-7 cyclohexenone 
• 1765-93-1 4-fluoroboronic acid 
• 352-13-6 4-flourophenylmagnesium bromide 
• 1546-11-8 4'-fluoro-2,3,4,5-tetrahydro-1,1'-biphenyl 
• 1496-36-2 1-(4-fluorophenyl)cyclohexan-1-ol 
• 462-06-6 fluorobenzene 

Downstream Products

• 1147417-08-0 methyl [4-(4-fluorophenyl)-2-oxocyclohex-3-en-1-yl](oxo)acetate 
• 1613527-37-9 N-(5-(4-fluorophenyl)cyclohexa-1,5-dienyl)acetamide 
• 1613527-17-5 N-(3-(4-fluorophenyl)cyclohex-2-enyl)acetamide 
• 1186225-50-2 3-(4-fluorophenyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohexanone 
• 10540-41-7 4'-fluoro-[1,1'-biphenyl]-3-ol 

Relevant articles and documents

Visible light promoted allylic C-H oxidation

A mild and efficient one-pot visible light-induced method has been developed for the allylic oxidation. The oxidation of allylic systems has played a prominent role in this context as possibly the most widely applied C-H functionalization, owing to the utility of enones. The allylic C-H oxidation is relatively simple and predictable, even on a preparative scale, because active species generated at the allylic position are stabilized by the double bond.

Synthesis of chiral seven-membered β-substituted lactams: Via Rh-catalyzed asymmetric hydrogenation

Rh/bisphosphine-thiourea ligand (ZhaoPhos)-catalyzed asymmetric hydrogenation of seven-membered β-substituted α,β-unsaturated lactams was successfully developed to prepare various chiral seven-membered β-substituted lactams with good to excellent results (up to >99% conversion, 99% yield, and >99% ee).

Copper/Selectfluor-System-Catalyzed Dehydration-Oxidation of Tertiary Cycloalcohols: Access to β-Substituted Cyclohex-2-enones, 4-Arylcoumarins, and Biaryls

A route to β-substituted cyclohex-2-enones, 4-arylcoumarins, and biaryls has been developed. This approach involves a one-pot Cu0/Selectfluor-catalyzed dehydration-oxidation of tertiary cycloalcohols. Thus, by using 2 equiv. of Selectfluor at 25 C, the dehydration-oxidation of tertiary cyclohexanols and oxabenzocyclohexanols gave β-substituted cyclohex-2-enones and 4-arylcoumarins, respectively; whereas the dehydration-oxidation of tertiary cyclohexanols gave biaryls as the final products by using 2.5 equiv. of Selectfluor at 80 C. A route to β-substituted cyclohex-2-enones, 4-arylcoumarins, and biaryls has been developed. This approach involves a one-pot Cu0/Selectfluor-catalyzed dehydration-oxidation of tertiary cycloalcohols.