1546-11-8

Usage

Explanation

The compound consists of 12 carbon atoms, 13 hydrogen atoms, and 1 fluorine atom.

Explanation

The core structure is a benzene ring with a fluorine atom attached to the fourth carbon. A cyclohexene group is connected to the first carbon of the benzene ring.

Explanation

It is an aromatic compound containing a fluorine atom, which is part of the benzene ring.

Explanation

The compound has a liquid state under normal environmental conditions, with no color.

Explanation

It serves as a starting material or intermediate in the synthesis of various organic compounds, particularly in the pharmaceutical industry.

Explanation

The compound is used to produce different organic compounds through various chemical reactions.

Explanation

The specific arrangement of atoms in the molecule makes it useful for creating novel pharmaceuticals and other materials with potential applications.

Molecular structure

Benzene ring substituted with a fluorine atom at the 4th position and a cyclohexene group at the 1st position.

Type of compound

Fluoroaromatic compound

Physical state

Clear, colorless liquid at room temperature

Usage

Building block in organic synthesis and pharmaceutical research

Application

Reagent in chemical reactions

Unique molecular structure

Valuable tool in the development of new drugs and materials

Upstream product

• 1496-36-2 1-(4-fluorophenyl)cyclohexan-1-ol 
• 108-94-1 cyclohexanone 
• 352-13-6 4-flourophenylmagnesium bromide 
• 1765-93-1 4-fluoroboronic acid 
• 109467-74-5 phosphoric acid cyclohex-1-enyl ester diphenyl ester 
• 7570-92-5 cyclohexyl phenyl sulphide 
• 460-00-4 1-Bromo-4-fluorobenzene 

Downstream Products

• 1717-84-6 1-cyclohexyl-4-fluorobenzene 
• 129501-17-3 2-bromo-1-(4-fluorophenyl)cyclohexanol 
• 60652-13-3 (1R,2R)-1-(4-Fluoro-phenyl)-cyclohexane-1,2-diol 
• 100199-31-3 trans-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)cyclohexanol 
• 898767-09-4 6-(4-fluorophenyl)-6-oxohexanenitrile 
• 111945-91-6 4'-fluoro-5,6-dihydro-[1,1'-biphenyl]-3(4H)-one 

Relevant academic research and scientific papers

Photocatalyzed Transition-Metal-Free Oxidative Cross-Coupling Reactions of Tetraorganoborates**

Readily accessible tetraorganoborate salts undergo selective coupling reactions under blue light irradiation in the presence of catalytic amounts of transition-metal-free acridinium photocatalysts to furnish unsymmetrical biaryls, heterobiaryls and arylated olefins. This represents an interesting conceptual approach to forge C?C bonds between aryl, heteroaryl and alkenyl groups under smooth photochemical conditions. Computational studies were conducted to investigate the mechanism of the transformation.

Electro-Olefination—A Catalyst Free Stereoconvergent Strategy for the Functionalization of Alkenes

Conventional methods carrying out C(sp2)?C(sp2) bond formations are typically mediated by transition-metal-based catalysts. Herein, we conceptualize a complementary avenue to access such bonds by exploiting the potential of electrochemistry in combination with organoboron chemistry. We demonstrate a transition metal catalyst-free electrocoupling between (hetero)aryls and alkenes through readily available alkenyl-tri(hetero)aryl borate salts (ATBs) in a stereoconvergent fashion. This unprecedented transformation was investigated theoretically and experimentally and led to a library of functionalized alkenes. The concept was then carried further and applied to the synthesis of the natural product pinosylvin and the derivatization of the steroidal dehydroepiandrosterone (DHEA) scaffold.

Catalytic hydrogen atom transfer (HAT) for sustainable and diastereoselective radical reduction

Going cyclic! A catalytic cycle and cyclic transition states enable a novel sustainable and catalytic hydrogen atom transfer (HAT) for highly diastereoselective radical reductions. Readily available nontoxic silanes are the terminal reductants for epoxides that are opened by bifunctional titanocene(III) hydride catalysts. Copyright

Nickel-catalyzed alkenylative cross-coupling reaction of alkyl sulfides

A novel cross-coupling reaction of alkyl aryl sulfides with aryl Grignard reagents has been achieved to produce the alkenyl-aryl coupling products in high yields by using catalytic Ni(cod)2 and a bulky N-heterocyclic carbene ligand, SIPr.

Nickel-catalyzed cross-couplings of cyclohexenyl phosphate and arylboronic acids

The Nickel-catalyzed cross-coupling reaction of cyclohexenylphosphate with a variety of arylboronic acids is described here for the first time. This methodology opens the door to other palladium or nickel-catalyzed coupling reactions involving vinyl phosphates.