112122-42-6Relevant articles and documents
TfOH-Catalyzed One-Pot Domino Reaction for Diastereoselective Synthesis of Polysubstituted Tetrahydrospiro[carbazole-1,3′-indoline]s
Yang, Ren-Yin,Sun, Jing,Tao, Yao,Sun, Qiu,Yan, Chao-Guo
, p. 13277 - 13287 (2017)
TfOH-catalyzed one-pot sequential reaction of indoles, acetophenones (cyclic ketones), and various 3-methyleneoxindolines in toluene afforded polysubstituted tetrahydrospiro[carbazole-1,3′-indoline]s in satisfactory yields. 1H NMR spectra and s
Three-Component Cascade Synthesis of Carbazoles through [1s,6s] Sigmatropic Shift under Metal-Free Conditions
Chen, Shanping,Jiang, Pingyu,Wang, Pu,Pei, Yong,Huang, Huawen,Xiao, Fuhong,Deng, Guo-Jun
, p. 3121 - 3131 (2019)
A novel method was developed for the synthesis of substituted carbazoles from commercially available starting materials under metal-free conditions. This strategy involves a [1s,6s] sigmatropic shift step and introduces an electron-withdrawing ester substituent at the C2 position of the carbazole ring. The present protocol afforded the desired carbazole derivatives with good regioselectivity and well functional group tolerance. DFT calculations were carried out to support the reaction pathway.
Selectivity control in gold-catalyzed hydroarylation of alkynes with indoles: Application to unsymmetrical bis(indolyl)methanes
McLean, Euan B.,Cutolo, Francesca M.,Cassidy, Orla J.,Burns, David J.,Lee, Ai-Lan
, p. 6977 - 6981 (2020/09/12)
Gold-catalyzed hydroarylation of unactivated alkynes with indoles have previously been reported to proceed with double indole addition to produce symmetrical bis(indolyl)methanes (BIMs). We demonstrate for the first time that the selectivity of the gold-c
