112146-46-0

Basic information

• Product Name: 2-benzyloxycarbonylamino-3-O-chloroacetyl-2-deoxy-4,6-O-ethylidene-α-D-glucopyranose
• CAS NO: 112146-46-0
• Molecular Weight: 415.828
• Mol File: 112146-46-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-benzyloxycarbonylamino-3-O-chloroacetyl-2-deoxy-4,6-O-ethylidene-α-D-glucopyranose(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzyloxycarbonylamino-3-O-chloroacetyl-2-deoxy-4,6-O-ethylidene-α-D-glucopyranose(112146-46-0)
• EPA Substance Registry System: 2-benzyloxycarbonylamino-3-O-chloroacetyl-2-deoxy-4,6-O-ethylidene-α-D-glucopyranose(112146-46-0)

Safety Data

• Hazardous Substances Data: 112146-46-0(Hazardous Substances Data)

Upstream product

• 131118-80-4 2-benzyloxycarbonylamino-1,3-di-O-chloroacetyl-2-deoxy-4,6-O-ethylidene-α/β-D-glucopyranose 

Downstream Products

• 105655-99-0 4'-O-demethyl-4-O-(2-deoxy-2-dimethylamino-4,6-O-ethylidene-α-D-glucopyranosyl)-4-epipodophyllotoxin 
• 105656-01-7 4-O-(2-amino-2-deoxy-4,6-O-ethylidene-α-D-glucopyranosyl)-4'-O-demethyl-4-epipodophyllotoxin 
• 111275-60-6 4'-O-benzyloxycarbonyl-4-O-(2-benzyloxycarbonylamino-2-deoxy-4,6-O-ethylidene-α-D-glucopyranosyl)-4'-O-demethyl-4-epipodophyllotoxin 
• 131118-83-7 4'-O-benzyloxycarbonyl-4-O-(2-benzyloxycarbonylamino-3-O-chloroacetyl-2-deoxy-4,6-O-ethylidene-α-D-glucopyranosyl)-4'-O-demethyl-4-epipodophyllotoxin 
• 105655-99-0 4'-O-demethyl-4-O-(2-deoxy-2-dimethylamino-4,6-O-ethylidene-β-D-glucopyranosyl)-4-epipodophyllotoxin 
• 105656-01-7 4-O-(2-amino-2-deoxy-4,6-O-ethylidene-β-D-glucopyranosyl)-4'-O-demethyl-4-epipodophyllotoxin 
• 111275-60-6 4'-O-benzyloxycarbonyl-4-O-(2-benzyloxycarbonylamino-2-deoxy-4,6-O-ethylidene-β-D-glucopyranosyl)-4'-O-demethyl-4-epipodophyllotoxin 
• 131118-85-9 4-O-(2-benzyloxycarbonylamino-2-deoxy-4,6-O-ethylidene-β-D-glucopyranosyl)-4'-O-demethyl-4-epipodophyllotoxin 
• 131118-84-8 4-O-(2-benzyloxycarbonylamino-3-O-chloroacetyl-2-deoxy-4,6-O-ethylidene-β-D-glucopyranosyl)-4-epipodophyllotoxin 
• 131118-84-8 4-O-(2-benzyloxycarbonylamino-3-O-chloroacetyl-2-deoxy-4,6-O-ethylidene-α-D-glucopyranosyl)-4-epipodophyllotoxin 
• 131118-83-7 4'-O-benzyloxycarbonyl-4-O-(2-benzyloxycarbonylamino-3-O-chloroacetyl-2-deoxy-4,6-O-ethylidene-β-D-glucopyranosyl)-4'-O-demethyl-4-epipodophyllotoxin 

Relevant articles and documents

Etoposide: a new approach to the synthesis of 4-O-(2-amino-2-deoxy-4,6-O-ethylidene-β-D-glucopyranosyl)-4'-O-demethyl-4-epipodophyllotoxin

Synthesis of 3-O-acetyl-2-benzyloxycarbonylamino-2-deoxy-4,6-O-ethylidene-α-(7α) and -β-D-glucopyranose (7β) and their 3-O-chloroacetyl analogues (11α and 11β) are described.Condensation (BF3-etherate, ethyl acetate, -20 deg C) of 7α with 4'-O-benzyloxyca